{"id":"W4415282217","doi":"10.3390/pathogens14101049","title":"Efficacy and Safety of Voriconazole for Difficult-to-Treat Distal Lateral Subungual Onychomycosis (DLSO)","year":2025,"lang":"en","type":"article","venue":"Pathogens","topic":"Nail Diseases and Treatments","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University; University of Toronto","funders":"","keywords":"Voriconazole; Terbinafine; Itraconazole; Refractory (planetary science); Cure rate; Azole; Antifungal","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00003733458,0.0001416894,0.0002911804,0.00007891825,0.00006840631,0.000009829926,0.00004033835,0.0000482947,0.00002843197],"category_scores_gemma":[0.00008250757,0.0001096664,0.0001106801,0.0001728392,0.0000320501,0.00002071843,0.00004290699,0.00003541711,0.000006560984],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004765472,"about_ca_system_score_gemma":0.00004872478,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002757231,"about_ca_topic_score_gemma":0.000008652994,"domain_scores_codex":[0.9992281,0.00001393782,0.0002048808,0.0002488801,0.0001014103,0.0002027803],"domain_scores_gemma":[0.9994247,0.00009761863,0.00003559934,0.0001968386,0.00008368987,0.0001615457],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.006251263,0.002180448,0.8745636,0.0006188513,0.000516068,0.00006481964,0.0005270909,0.000005740267,0.04722526,0.002168938,0.00167193,0.06420604],"study_design_scores_gemma":[0.006706041,0.0003762275,0.9854116,0.0001169518,0.000658354,0.000006844279,0.00005244085,0.00003801826,0.00394081,0.00007030611,0.002515109,0.0001073064],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9961593,0.000601563,0.0002480016,0.0003110325,0.0000916791,0.000802444,0.000802031,0.00003025517,0.0009537109],"genre_scores_gemma":[0.9972249,0.00005456447,0.000413236,0.0001226988,0.00004422726,0.0000511518,0.0001935238,0.00001377866,0.001881942],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.110848,"threshold_uncertainty_score":0.4472064,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009087901403821251,"score_gpt":0.2878178268834669,"score_spread":0.2787299254796456,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}