{"id":"W4415311518","doi":"10.1007/s00203-025-04526-6","title":"Intranasal phage therapy overcomes antibody neutralization challenges in pulmonary Pseudomonas aeruginosa infections","year":2025,"lang":"en","type":"article","venue":"Archives of Microbiology","topic":"Bacteriophages and microbial interactions","field":"Environmental Science","cited_by":3,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Nasal administration; Pseudomonas aeruginosa; Antibody; Immune system; Lung; Phage therapy; Bronchoalveolar lavage; Neutralization","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002667517,0.0003370667,0.0005264374,0.0001553056,0.000286958,0.0004851182,0.0003493525,0.0004870663,0.001284556],"category_scores_gemma":[0.0003090989,0.0001487664,0.0002135937,0.00006804183,0.0003514547,0.0002902477,0.0002393822,0.001221789,0.0002369579],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001609465,"about_ca_system_score_gemma":0.0003619227,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006430685,"about_ca_topic_score_gemma":0.001439129,"domain_scores_codex":[0.9997861,0.00003961486,0.000009288218,0.0000262931,0.00004463173,0.00009418957],"domain_scores_gemma":[0.9998584,0.00003543647,0.00002050847,0.00001535416,0.00001100618,0.00005933785],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002179058,0.001749085,0.0006324658,0.0001102833,0.00002246684,0.0001612542,0.00009370328,0.0002554003,0.9660855,0.0001666202,0.0003203068,0.02822389],"study_design_scores_gemma":[0.0009337651,0.05709971,0.02870925,0.00008010249,0.0001461658,0.001866254,0.0003931765,0.005877619,0.8976191,0.0003311208,0.006915427,0.00002839846],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9965277,0.001337964,0.0009429703,0.000132431,0.00008567026,0.00003828076,0.00002156746,0.00006437355,0.0008490695],"genre_scores_gemma":[0.9974205,0.0005387537,0.0005244602,0.00005113712,0.000040304,0.00002052753,0.00003943751,0.000007646564,0.001357151],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001284556,"threshold_uncertainty_score":0.004297316,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01300010559915346,"score_gpt":0.268644723189719,"score_spread":0.2556446175905656,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}