{"id":"W4415323881","doi":"10.7759/cureus.94838","title":"Evaluation of Polmacoxib 2 mg for the Management of Hip and Knee Osteoarthritis: A Prospective, Single-Arm, Multicenter, Open-Label Study","year":2025,"lang":"en","type":"article","venue":"Cureus","topic":"Inflammatory mediators and NSAID effects","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Tolerability; Osteoarthritis; Adverse effect; Safety profile; Clinical trial","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002854021,0.001082077,0.0020293,0.0004624338,0.0004181869,0.0007290599,0.0006840621,0.0007804143,0.001862603],"category_scores_gemma":[0.001314171,0.0005190221,0.001335435,0.0006035972,0.0007709273,0.0007608812,0.0002615429,0.001308319,0.0004137383],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004599857,"about_ca_system_score_gemma":0.00119098,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004934354,"about_ca_topic_score_gemma":0.0009075038,"domain_scores_codex":[0.999103,0.0004560664,0.00008538464,0.0001332309,0.0001340489,0.00008836648],"domain_scores_gemma":[0.9984974,0.0002406338,0.0005645352,0.0001131133,0.0001608796,0.0004234446],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.7207434,0.1016728,0.03800648,0.001846374,0.002370279,0.0003852634,0.0004543593,0.0007615743,0.05872583,0.0001301385,0.000873709,0.0740298],"study_design_scores_gemma":[0.2328322,0.708297,0.05212259,0.00005455607,0.001174378,0.0003615567,0.0001042755,0.0006644924,0.00302882,0.00003996698,0.001278237,0.00004195912],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9954638,0.002215622,0.0003019175,0.00008531957,0.00004104604,0.001224659,0.0002907225,0.00002724084,0.00034977],"genre_scores_gemma":[0.9937674,0.001846571,0.001090901,0.0004230478,0.0002035138,0.001381012,0.0007798204,0.000009322024,0.0004985447],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002854021,"threshold_uncertainty_score":0.01509368,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05321824710927474,"score_gpt":0.3620232303300476,"score_spread":0.3088049832207728,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}