{"id":"W4415351069","doi":"10.7554/elife.106549","title":"Resident memory macrophages and trained innate immunity at barrier tissues","year":2025,"lang":"en","type":"review","venue":"eLife","topic":"Immune responses and vaccinations","field":"Immunology and Microbiology","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"Canadian Institutes of Health Research; National Sanitarium Association","keywords":"Innate immune system; Innate lymphoid cell; Immune system; Reprogramming; Inflammation; Immunity; Acquired immune system; Haematopoiesis","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0004409041,0.0004084042,0.001274806,0.000325366,0.0005257429,0.00003195962,0.0003484625,0.0006090341,0.001948778],"category_scores_gemma":[0.0004133717,0.0003311961,0.0003085629,0.0002184195,0.0001383332,0.0000499714,0.0005228568,0.0005937532,0.0005394652],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001069954,"about_ca_system_score_gemma":0.0003069657,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001133752,"about_ca_topic_score_gemma":0.00003527268,"domain_scores_codex":[0.9977147,0.00093696,0.0005720521,0.0003750394,0.00004367888,0.0003575846],"domain_scores_gemma":[0.9984366,0.0006805199,0.0002260829,0.0005554656,0.00007176388,0.00002955264],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00009111835,0.00005268289,0.000005176789,0.00651934,0.001225097,0.00003275976,0.0005351479,8.197421e-8,0.0003168266,0.0003198025,0.03248459,0.9584174],"study_design_scores_gemma":[0.0004611881,0.00005033754,0.0001117483,0.002789815,0.0005275116,0.000113542,0.00007478511,4.882018e-8,0.0006408794,0.000009673366,0.9949233,0.0002971649],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0003425867,0.9960639,0.000002932308,0.00008454767,0.0007436095,0.0005750998,0.0002466882,0.00008464373,0.001855933],"genre_scores_gemma":[0.00008593725,0.8298107,0.00001350092,0.00006760899,0.0000329785,0.0000848397,0.0003663594,0.00002751533,0.1695106],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9624387,"threshold_uncertainty_score":0.999914,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02220894630055639,"score_gpt":0.3233999503839387,"score_spread":0.3011910040833823,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}