{"id":"W4415382150","doi":"10.1016/j.gtc.2025.08.002","title":"Biomarkers in Irritable Bowel Syndrome","year":2025,"lang":"en","type":"article","venue":"Gastroenterology Clinics of North America","topic":"Gastrointestinal motility and disorders","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Bausch Health; AbbVie","keywords":"Irritable bowel syndrome; Intestinal permeability; Microbiome; Small intestinal bacterial overgrowth; Dysbiosis; Biomarker; DNA methylation; Inflammatory Bowel Diseases","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007058794,0.0007893209,0.0009249569,0.003297557,0.000459353,0.001668166,0.0003263275,0.0008908915,0.001504729],"category_scores_gemma":[0.002476519,0.0002602884,0.000436717,0.002558117,0.0003179695,0.0007736193,0.0006115696,0.0008727221,0.0005141895],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004662985,"about_ca_system_score_gemma":0.0005347808,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001029685,"about_ca_topic_score_gemma":0.001004484,"domain_scores_codex":[0.9994142,0.0001946628,0.0001164264,0.00006228787,0.000145276,0.00006720975],"domain_scores_gemma":[0.9987962,0.0002698828,0.0005146691,0.00003073714,0.0002377566,0.0001506187],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001450991,0.0003919954,0.7772774,0.001739193,0.0006079829,0.003486892,0.0002103847,0.0006310171,0.008928912,0.002979578,0.0119835,0.1903121],"study_design_scores_gemma":[0.0002186737,0.001561936,0.8831428,0.002682525,0.0007931239,0.01162641,0.0008085837,0.002205271,0.006495933,0.007019633,0.08335039,0.00009472054],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.4294905,0.5220602,0.002819328,0.009572993,0.003737777,0.0001757405,0.002818291,0.0001869562,0.02913811],"genre_scores_gemma":[0.9112466,0.07179796,0.005713406,0.002673666,0.002578303,0.0001980801,0.001626974,0.00002577009,0.004139188],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003297557,"threshold_uncertainty_score":0.005033791,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009739350099715502,"score_gpt":0.276441813208108,"score_spread":0.2667024631083925,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}