{"id":"W4415383220","doi":"10.1186/s12864-025-12112-9","title":"Building a bovine blood DNA methylation epimap related to disease phenotypes","year":2025,"lang":"en","type":"article","venue":"BMC Genomics","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"Defence Research and Development Canada; University of British Columbia; Université Laval; Intertek (Canada)","funders":"Genome Canada","keywords":"Phenotype; DNA methylation; Immune system; Gene; Transcription factor; Disease; Transcription (linguistics); DNA microarray; DNA","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007950368,0.000476649,0.0006530405,0.002714074,0.0005192776,0.0008989598,0.0005389431,0.0005222094,0.005177551],"category_scores_gemma":[0.001690628,0.0003880321,0.0007306774,0.001952839,0.0002011341,0.0003038105,0.001095862,0.0005544682,0.001257193],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005908644,"about_ca_system_score_gemma":0.0007364223,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01531354,"about_ca_topic_score_gemma":0.02331258,"domain_scores_codex":[0.9994729,0.00008307798,0.00002036945,0.0002741967,0.00005791879,0.00009149373],"domain_scores_gemma":[0.9993858,0.0002034091,0.0001214542,0.00006521765,0.0001563764,0.00006765761],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001150577,0.0001021347,0.582101,0.0009760741,0.0008552279,0.0004864504,0.001015719,0.01411571,0.1666751,0.001871913,0.009989954,0.2206602],"study_design_scores_gemma":[0.00009775317,0.0004109205,0.8826828,0.0002704839,0.0008590323,0.0008387537,0.000447345,0.04582806,0.01240442,0.00524074,0.05084274,0.00007690785],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7281598,0.008701792,0.1826076,0.0008040206,0.0001031969,0.0002786273,0.0690438,0.002320792,0.007980307],"genre_scores_gemma":[0.7936066,0.00246724,0.1291362,0.0006025703,0.00006614251,0.0004479135,0.06911217,0.0004259917,0.00413514],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01531354,"threshold_uncertainty_score":0.03044879,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009613999973388937,"score_gpt":0.2669335540710827,"score_spread":0.2573195540976937,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}