{"id":"W4415387269","doi":"10.1002/dneu.23010","title":"Administering MSC‐Derived Exosomes After Hypoxia‐Induced Seizures in Neonatal Rats Improved Cognitive Function and Delayed the Onset of Epilepsy in Adulthood, Likely by Reducing Inflammation and Oxidative Stress","year":2025,"lang":"en","type":"article","venue":"Developmental Neurobiology","topic":"Neonatal and fetal brain pathology","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"University Health Network","funders":"Ahvaz Jundishapur University of Medical Sciences","keywords":"Oxidative stress; Neuroprotection; Hypoxia (environmental); Microvesicles; Epilepsy; Hippocampal formation; Inflammation; Pathological; Exosome","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001074005,0.0003565399,0.0003776939,0.0002148154,0.00008748698,0.0001353268,0.0001270103,0.0002757233,0.0009083828],"category_scores_gemma":[0.00009872713,0.00009231746,0.0002851431,0.00009330648,0.0002194511,0.0002541295,0.0001962055,0.0005381076,0.0001212204],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001198574,"about_ca_system_score_gemma":0.0002136872,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003966854,"about_ca_topic_score_gemma":0.0007526678,"domain_scores_codex":[0.9999173,0.000008372019,0.00001186088,0.00001410338,0.00001929817,0.0000289701],"domain_scores_gemma":[0.9998971,0.000006325687,0.00003495138,0.000008893499,0.00001637829,0.00003635796],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008490597,0.000140409,0.0004152338,0.0000862713,0.00001569006,0.00006219123,0.00002396047,0.00005677246,0.9939564,0.00007089151,0.00007129389,0.004251935],"study_design_scores_gemma":[0.00004999268,0.003137259,0.00723379,0.0000165472,0.0000443735,0.0001320039,0.00006264766,0.0003222315,0.987305,0.00005026369,0.001639056,0.000006837109],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9974114,0.0006312219,0.001137527,0.00008635967,0.0000419145,0.00002542194,0.0003088918,0.00004160411,0.0003155229],"genre_scores_gemma":[0.9956266,0.0008784508,0.001244335,0.0000598419,0.0000160718,0.00008206969,0.000374861,0.00000779185,0.001710043],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009083828,"threshold_uncertainty_score":0.003038824,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009309579645350166,"score_gpt":0.2400736413351272,"score_spread":0.230764061689777,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}