{"id":"W4415407744","doi":"10.1093/nar/gkaf1028","title":"Structural insights into γH2Ax containing nucleosomes","year":2025,"lang":"en","type":"article","venue":"Nucleic Acids Research","topic":"DNA Repair Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"St. Francis Xavier University; University of Alberta; Memorial University of Newfoundland","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; National Institutes of Health","keywords":"Nucleosome; Histone; Chromatin; DNA; Phosphorylation; Histone H2B; Protein structure; DNA repair","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007925752,0.0002302572,0.0001386156,0.0001789937,0.0001882549,0.0002654727,0.0002641527,0.0003107056,0.001653378],"category_scores_gemma":[0.0001258085,0.0002169049,0.0001231153,0.0001618577,0.0001737574,0.0003568682,0.0001900701,0.0003648241,0.0002988572],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002256327,"about_ca_system_score_gemma":0.0001347934,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001157442,"about_ca_topic_score_gemma":0.002016829,"domain_scores_codex":[0.9999701,0.00000397235,0.000001485282,0.000009055319,0.000009313889,0.000006115862],"domain_scores_gemma":[0.9999635,0.00001122907,0.000007434325,0.000005012224,0.000004461707,0.000008438523],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001330331,0.00004107839,0.003313647,0.0002239416,0.00003107326,0.0004875285,0.0002142694,0.009598779,0.9740572,0.003677491,0.000308446,0.007913418],"study_design_scores_gemma":[0.00006246054,0.0005225285,0.07991324,0.0001253232,0.0001520462,0.002891178,0.001116257,0.1107172,0.7507507,0.01370237,0.03996011,0.00008661034],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9736214,0.004177636,0.01759064,0.0002142805,0.00003269777,0.000008080395,0.000347553,0.0001618644,0.003845944],"genre_scores_gemma":[0.9911833,0.001423597,0.005870609,0.00006078977,0.000008453426,0.000006054593,0.0004640227,0.00001648409,0.0009667189],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001653378,"threshold_uncertainty_score":0.005531073,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02492128903919549,"score_gpt":0.3402910820804765,"score_spread":0.315369793041281,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}