{"id":"W4415436696","doi":"10.1002/cncr.35947","title":"Defining and measuring tolerability in pediatric, adolescent, and young adult oncology: The essential voices","year":2025,"lang":"en","type":"review","venue":"Cancer","topic":"Childhood Cancer Survivors' Quality of Life","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children","funders":"National Cancer Institute","keywords":"Tolerability; Clinical trial; Young adult; Clinical significance; MEDLINE; Generalizability theory; Pediatric oncology; Relevance (law)","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00800195,0.0008100217,0.002574312,0.002035859,0.0003659033,0.002613053,0.0009032342,0.00129896,0.0009778058],"category_scores_gemma":[0.01351791,0.0003297284,0.001678642,0.002378516,0.001222906,0.002823476,0.001236435,0.002660349,0.0002317211],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001286059,"about_ca_system_score_gemma":0.003327125,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002839516,"about_ca_topic_score_gemma":0.004554425,"domain_scores_codex":[0.995883,0.002230257,0.0007583423,0.0002215303,0.0008047997,0.0001021084],"domain_scores_gemma":[0.9857227,0.01159107,0.001251745,0.0002100576,0.001104289,0.0001200919],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.0001010729,0.00005668371,0.002154535,0.07201421,0.0005275012,0.0001024406,0.000745433,0.0002662694,0.0003058964,0.006687884,0.00811273,0.9089254],"study_design_scores_gemma":[0.00007715114,0.0006653103,0.02242656,0.2604858,0.00293677,0.003206057,0.00350036,0.000495101,0.001115979,0.01304996,0.6918754,0.0001655273],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002484848,0.9983509,0.0002350992,0.0006009816,0.0001180605,0.00001590627,0.00002005931,0.000002155483,0.0004083118],"genre_scores_gemma":[0.005129714,0.9928132,0.0009936475,0.0006858656,0.0001861187,0.00004616701,0.00003591368,0.000002660539,0.0001067268],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.00800195,"threshold_uncertainty_score":0.04231888,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04514045849692151,"score_gpt":0.3828542340548805,"score_spread":0.337713775557959,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}