{"id":"W4415458860","doi":"10.1186/s40168-025-02184-w","title":"Host miRNAs regulate Escherichia coli O157 mucosal colonization through host-mucosa-attached microbiota interactions in calves","year":2025,"lang":"en","type":"article","venue":"Microbiome","topic":"Escherichia coli research studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Agriculture and Agri-Food Canada; University of British Columbia; University of Alberta","funders":"Natural Sciences and Engineering Research Council of Canada; Beef Cattle Research Council; European Commission; University of Alberta","keywords":"Colonization; Virulence; Host (biology); Pathogen; Virulence factor; Crosstalk; Escherichia coli; Host factors; Microbiome","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003046217,0.0003315456,0.0004574707,0.0003929156,0.0002289627,0.0007610897,0.0002171579,0.0004334559,0.0011058],"category_scores_gemma":[0.0004380575,0.000233057,0.0003866665,0.0002091639,0.0002936787,0.0003575691,0.0004196609,0.0006496799,0.0002681521],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005884245,"about_ca_system_score_gemma":0.0003949949,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001995892,"about_ca_topic_score_gemma":0.002863637,"domain_scores_codex":[0.9994851,0.00007027214,0.00002424856,0.000159053,0.0001282706,0.000132905],"domain_scores_gemma":[0.9996965,0.00005358296,0.00009625738,0.00001728944,0.00006531605,0.00007104738],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006957118,0.00006188294,0.007828213,0.0001071355,0.00002037598,0.0001100196,0.0001469405,0.000124856,0.9872894,0.00007464585,0.00005808409,0.003482768],"study_design_scores_gemma":[0.00006033129,0.003620951,0.309409,0.00009407257,0.0002881534,0.0006939702,0.001429001,0.005213794,0.6718233,0.000408061,0.006884933,0.00007453992],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9954869,0.001561696,0.001766342,0.00004484452,0.00002038621,0.00002182602,0.000541634,0.00002757213,0.0005287416],"genre_scores_gemma":[0.995214,0.0008750334,0.001506018,0.00008730163,0.000008655019,0.00004868089,0.0005360135,0.00001952655,0.001704803],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001995892,"threshold_uncertainty_score":0.004269421,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01345534893765042,"score_gpt":0.3115588806507004,"score_spread":0.2981035317130499,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}