{"id":"W4415462586","doi":"10.1038/s41433-025-04059-8","title":"Real-world treatment patterns and visual outcomes of faricimab in patients with diabetic macular oedema in the UK at 12 months: the FARWIDE-DMO study","year":2025,"lang":"en","type":"article","venue":"Eye","topic":"Retinal Diseases and Treatments","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"Roche (Canada)","funders":"National Institute for Health Research Biomedical Research Centre at Moorfields Eye Hospital NHS Foundation Trust and UCL Institute of Ophthalmology; Genentech; Liverpool University Hospitals NHS Foundation Trust; Queen's University; Queen's University Belfast; Cardiff University; Moorfields Eye Hospital NHS Foundation Trust; University of Oxford; University of Southampton; Oxford University Hospitals NHS Foundation Trust; University Hospitals Bristol NHS Foundation Trust; Royal Free London NHS Foundation Trust; National Institute for Health and Care Research; University Hospital Southampton NHS Foundation Trust; Sheffield Teaching Hospitals NHS Foundation Trust; F. Hoffmann-La Roche","keywords":"Visual acuity; Diabetic retinopathy; MEDLINE; Multicenter study; Eye disease; Diabetes mellitus","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00205807,0.0004086149,0.0008865513,0.0009815851,0.0002806157,0.001148589,0.0005253417,0.0007273167,0.0009499399],"category_scores_gemma":[0.006609693,0.0003566425,0.00136245,0.002060026,0.000332319,0.0007369916,0.001008015,0.0005769757,0.0002198578],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008145735,"about_ca_system_score_gemma":0.000417064,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.008784808,"about_ca_topic_score_gemma":0.01118983,"domain_scores_codex":[0.9972528,0.00105053,0.0005813348,0.0004630641,0.0004134936,0.0002387967],"domain_scores_gemma":[0.9899248,0.001243024,0.007299584,0.0004204035,0.0005810793,0.0005310617],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001951503,0.00006133474,0.9943345,0.0001481427,0.0006013021,0.00007358442,0.00009994281,0.00006681019,0.0001112861,0.00001243238,0.0002121685,0.00232708],"study_design_scores_gemma":[0.000131207,0.0003826139,0.9984882,0.00006531604,0.0002271007,0.0002140803,0.0001224047,0.00006891666,0.00002653077,0.00001077748,0.0002514418,0.00001153319],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9946128,0.003222556,0.00004717816,0.00007517789,0.000009751756,0.00002351629,0.0016526,0.000002421568,0.0003540693],"genre_scores_gemma":[0.9979805,0.0005487698,0.00005513726,0.00005812486,0.00001529594,0.00002397909,0.00123446,0.000001662952,0.00008201924],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.008784808,"threshold_uncertainty_score":0.01746732,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008850986553979295,"score_gpt":0.3012839890443011,"score_spread":0.2924330024903218,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}