{"id":"W4415462586","doi":"10.1038/s41433-025-04059-8","title":"Real-world treatment patterns and visual outcomes of faricimab in patients with diabetic macular oedema in the UK at 12 months: the FARWIDE-DMO study","year":2025,"lang":"en","type":"article","venue":"Eye","topic":"Retinal Diseases and Treatments","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"Roche (Canada)","funders":"National Institute for Health Research Biomedical Research Centre at Moorfields Eye Hospital NHS Foundation Trust and UCL Institute of Ophthalmology; Genentech; Liverpool University Hospitals NHS Foundation Trust; Queen's University; Queen's University Belfast; Cardiff University; Moorfields Eye Hospital NHS Foundation Trust; University of Oxford; University of Southampton; Oxford University Hospitals NHS Foundation Trust; University Hospitals Bristol NHS Foundation Trust; Royal Free London NHS Foundation Trust; National Institute for Health and Care Research; University Hospital Southampton NHS Foundation Trust; Sheffield Teaching Hospitals NHS Foundation Trust; F. Hoffmann-La Roche","keywords":"Visual acuity; Diabetic retinopathy; MEDLINE; Multicenter study; Eye disease; Diabetes mellitus","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008099988,0.000165378,0.0003377954,0.0001007454,0.00005039082,0.00001203125,0.00006481764,0.00001988243,0.00002189426],"category_scores_gemma":[0.00001562115,0.00007039684,0.00005580627,0.0001761963,0.00004161137,0.00001868948,0.00004874929,0.0000512916,0.000002082996],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001542421,"about_ca_system_score_gemma":0.0000253172,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.006833345,"about_ca_topic_score_gemma":0.006455879,"domain_scores_codex":[0.9990326,0.0001147482,0.0002320461,0.0002085897,0.0002415722,0.0001703984],"domain_scores_gemma":[0.9995131,0.0001186233,0.00006038459,0.0002606245,0.00002027071,0.00002697372],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0004098313,0.00279029,0.9920901,0.0000260626,0.0002612797,0.00006636022,0.001053593,0.000002222663,9.079719e-7,0.0000091594,0.00000804675,0.003282135],"study_design_scores_gemma":[0.006871427,0.001549713,0.9898764,0.00009887272,0.0003977733,1.541762e-7,0.001067798,0.00002758635,0.00001648737,0.00001435152,0.00002218437,0.00005719887],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9971045,0.0001572641,6.73906e-7,0.0004000091,0.00002232976,0.001642652,0.00001936007,0.000005980828,0.0006471996],"genre_scores_gemma":[0.9990219,0.0000411757,0.000003167924,0.0001648275,0.000003463404,0.0001634806,0.0000259209,0.000009279886,0.0005667772],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006461596,"threshold_uncertainty_score":0.9997802,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008850986553979295,"score_gpt":0.3012839890443011,"score_spread":0.2924330024903218,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}