{"id":"W4415462617","doi":"10.1177/15593258251391602","title":"Plasma miRNAome Profiling Reveals Candidate Biomarkers for Low- and High-Dose Whole-Body Ionizing Radiation Exposure","year":2025,"lang":"en","type":"article","venue":"Dose-Response","topic":"MicroRNA in disease regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Health Sciences North; Lakehead University; NOSM University; McMaster University; Laurentian University","funders":"","keywords":"Ionizing radiation; microRNA; Profiling (computer programming); Radiation exposure; Gene expression profiling; Biomarker","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004250114,0.0004398479,0.0003772157,0.0003925455,0.0001406352,0.0004076225,0.000162755,0.0005103431,0.001327188],"category_scores_gemma":[0.0004782905,0.0002122696,0.0003395615,0.0002304786,0.0002379727,0.0002394187,0.000267418,0.000529667,0.0004750666],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001593304,"about_ca_system_score_gemma":0.0001348024,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008404355,"about_ca_topic_score_gemma":0.0001345267,"domain_scores_codex":[0.999639,0.00007374756,0.00001919334,0.0001417082,0.00009559712,0.00003076681],"domain_scores_gemma":[0.9998023,0.00003829445,0.00008686779,0.00002267975,0.00002872313,0.00002116855],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004621889,0.00003142765,0.005030793,0.00006310313,0.00002563555,0.00003273926,0.00002344303,0.00008341705,0.9910529,0.00004174101,0.00005662676,0.003095977],"study_design_scores_gemma":[0.00005204172,0.002183535,0.1782359,0.00003204913,0.0002003166,0.0009195805,0.0001000053,0.002248797,0.8123661,0.0003182899,0.003319201,0.00002426953],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9771589,0.003230808,0.01734388,0.00009903408,0.00003774489,0.00007524006,0.0009298455,0.0002099032,0.0009146381],"genre_scores_gemma":[0.9869661,0.001072044,0.008793956,0.0001238257,0.00002360082,0.0001558382,0.0008542753,0.00004354214,0.001966757],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001327188,"threshold_uncertainty_score":0.00443989,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006756397227566145,"score_gpt":0.258815103814151,"score_spread":0.2520587065865849,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}