{"id":"W4415468626","doi":"10.1038/s41391-025-01038-8","title":"STEAP1-targeted strategies in advanced prostate cancer: a review on therapeutic and diagnostic implications","year":2025,"lang":"en","type":"article","venue":"Prostate Cancer and Prostatic Diseases","topic":"Prostate Cancer Treatment and Research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Health Sciences Centre; Sunnybrook Hospital; University of Toronto; Sunnybrook Health Science Centre","funders":"","keywords":"Prostate cancer; Prostate; Prostate disease; Disease; Therapeutic approach; Benign prostatic hyperplasia (BPH); Prostate-specific antigen; Prostatic disease","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001533662,0.0004042865,0.0006615876,0.0002654317,0.0002100761,0.000123995,0.00009955948,0.00005863656,0.00007335727],"category_scores_gemma":[0.0001922112,0.0003031143,0.00007016903,0.0007564101,0.0003308674,0.0002836449,0.00007459336,0.0002701949,0.000003540898],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002335936,"about_ca_system_score_gemma":0.001231963,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002932584,"about_ca_topic_score_gemma":0.0001080774,"domain_scores_codex":[0.9977882,0.0001008702,0.0004924166,0.0007371698,0.0002736972,0.0006076743],"domain_scores_gemma":[0.9985405,0.0004533858,0.0001296239,0.0003565651,0.0002156387,0.0003042738],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.002215037,0.0005117914,0.3726545,0.0153288,0.0002787845,0.00007129464,0.00109559,0.00004194174,0.0004666927,0.00133243,0.001650475,0.6043527],"study_design_scores_gemma":[0.01161471,0.001223925,0.9340411,0.0229538,0.001224161,0.00001339716,0.001580455,0.0002700047,0.0006441253,0.01197503,0.01368785,0.0007714339],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"review","genre_gemma":"empirical","genre_scores_codex":[0.2631779,0.7084163,0.000006403776,0.0205426,0.0001221548,0.005852401,0.001088263,0.0001413599,0.000652631],"genre_scores_gemma":[0.5364033,0.4531381,0.00005036392,0.002611629,0.00002077556,0.005894953,0.0001778059,0.00003293034,0.001670121],"genre_candidate":"review","genre_consensus":null,"teacher_disagreement_score":0.6035812,"threshold_uncertainty_score":0.9999421,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01948177346396031,"score_gpt":0.3711199151684267,"score_spread":0.3516381417044664,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}