{"id":"W4415474056","doi":"10.1128/mbio.02941-25","title":"Modulation of the <i>Pseudomonas aeruginosa</i> quorum sensing cascade by MexT-regulated factors","year":2025,"lang":"en","type":"article","venue":"mBio","topic":"Bacterial biofilms and quorum sensing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institut National de la Recherche Scientifique","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Institute of Allergy and Infectious Diseases; Canadian Institutes of Health Research; Cystic Fibrosis Foundation","keywords":"Quorum sensing; Operon; Transcription factor; Gene; Transcription (linguistics); Biofilm; Transcriptome; Efflux; Regulation of gene expression","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007624628,0.0001352936,0.0001380672,0.00002482556,0.0001121186,0.00002002566,0.0001097478,0.0001889682,0.000004254298],"category_scores_gemma":[0.00003876364,0.0001013389,0.0001065104,0.0001466294,0.00010926,0.000003316919,0.0001086289,0.0000706058,0.000001017269],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001429348,"about_ca_system_score_gemma":0.00004286206,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001798113,"about_ca_topic_score_gemma":0.00005505111,"domain_scores_codex":[0.999227,0.0000600559,0.000206414,0.0002304183,0.00008593812,0.0001902017],"domain_scores_gemma":[0.9994837,0.000008907374,0.00009743559,0.0003234108,0.00005783383,0.00002868322],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002337894,0.00001536415,0.001649505,0.000008817268,0.00003611777,1.971172e-7,0.00002519307,0.00002098246,0.9924124,0.00004610753,0.004024965,0.001736949],"study_design_scores_gemma":[0.0002357367,0.00002291043,0.01229679,0.00002804725,0.00002067584,0.000002461227,0.00003573174,0.0001437976,0.967325,0.00002592347,0.01975489,0.0001080282],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9977279,0.0002170548,0.000171732,0.0006172452,0.0004825392,0.0001322333,0.00003229019,0.00001237242,0.0006066444],"genre_scores_gemma":[0.9983487,0.00001627381,0.0001411075,0.000244001,0.00004958321,3.629052e-7,0.0001079405,0.00001171097,0.001080331],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02508742,"threshold_uncertainty_score":0.4132482,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005408835143769592,"score_gpt":0.2134193452192294,"score_spread":0.2080105100754598,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}