{"id":"W4415474868","doi":"10.1002/npr2.70066","title":"The Effect of N‐Acetylcysteine ( <scp>NAC</scp> ) on Neurometabolites and Cognitive Function in Adults With Alcohol Use Disorder: A Preliminary Randomized Controlled Trial","year":2025,"lang":"en","type":"article","venue":"Neuropsychopharmacology Reports","topic":"Alcoholism and Thiamine Deficiency","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"National Health and Medical Research Council; Medical Research Council; University of Sydney","keywords":"Randomized controlled trial; Cognition; Alcohol; Function (biology); Alcohol consumption","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001587125,0.0003953065,0.001952991,0.0004324371,0.0001482324,0.00002539759,0.00007116988,0.0001441601,0.000007411729],"category_scores_gemma":[0.006045928,0.0002110988,0.0002772449,0.0006198231,0.0005376356,0.0000987019,0.0000539732,0.0005346794,0.000001721961],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001033734,"about_ca_system_score_gemma":0.00009054957,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002742078,"about_ca_topic_score_gemma":0.000003932577,"domain_scores_codex":[0.9959015,0.001570766,0.001129844,0.0006887021,0.0003328359,0.0003763031],"domain_scores_gemma":[0.9871504,0.01150827,0.0007154412,0.0003464241,0.0001783636,0.0001010488],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9737234,0.0004646812,0.01962538,0.0001560246,0.0005337415,0.0009873025,0.0001195805,0.00001314938,0.001736925,0.00002322428,0.0002966046,0.002320027],"study_design_scores_gemma":[0.9339574,0.01267939,0.04784267,0.0002717545,0.003377181,0.0004008537,0.00004407008,0.0003489231,0.0005962129,0.00001520726,0.0003945711,0.00007177175],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9795691,0.003221674,0.00001927082,0.00027626,0.001890847,0.01258553,0.000004474101,0.00006281876,0.002370032],"genre_scores_gemma":[0.9952089,0.0007064617,0.00000449995,0.0005475173,0.00009842222,0.001878141,0.00001686521,0.00003362484,0.001505581],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03976596,"threshold_uncertainty_score":0.8608361,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005491139560733854,"score_gpt":0.2771678136539189,"score_spread":0.2716766740931851,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}