{"id":"W4415474868","doi":"10.1002/npr2.70066","title":"The Effect of N‐Acetylcysteine ( <scp>NAC</scp> ) on Neurometabolites and Cognitive Function in Adults With Alcohol Use Disorder: A Preliminary Randomized Controlled Trial","year":2025,"lang":"en","type":"article","venue":"Neuropsychopharmacology Reports","topic":"Alcoholism and Thiamine Deficiency","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"National Health and Medical Research Council; Medical Research Council; University of Sydney","keywords":"Randomized controlled trial; Cognition; Alcohol; Function (biology); Alcohol consumption","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001614423,0.001133525,0.002446325,0.0004469218,0.0005662169,0.0009134985,0.000746736,0.001669048,0.004548003],"category_scores_gemma":[0.001978697,0.0005123021,0.002020862,0.0004916991,0.0008749315,0.0008009185,0.0003419004,0.001745568,0.0005468832],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007259429,"about_ca_system_score_gemma":0.00149404,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002367809,"about_ca_topic_score_gemma":0.006051051,"domain_scores_codex":[0.9993092,0.0003465712,0.00009029735,0.0001161921,0.00005810004,0.00007961557],"domain_scores_gemma":[0.9987189,0.0003733929,0.0002546014,0.00007927156,0.0001655256,0.0004084586],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9816019,0.004238195,0.000541448,0.0007320524,0.001344222,0.00003590215,0.00003477484,0.00008543216,0.001956887,0.00003902011,0.000326263,0.009063945],"study_design_scores_gemma":[0.9231152,0.07241451,0.002443529,0.00005059396,0.0009037796,0.00002137595,0.00002574545,0.0002096118,0.0003291511,0.00005759719,0.0004185847,0.00001034609],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9807046,0.008834551,0.0005051357,0.0008101239,0.0005561243,0.006013493,0.0009580171,0.0001300058,0.001487903],"genre_scores_gemma":[0.986858,0.00382428,0.001523629,0.0006788214,0.0004059749,0.004437148,0.000558058,0.00001135318,0.001702735],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004548003,"threshold_uncertainty_score":0.01521462,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005491139560733854,"score_gpt":0.2771678136539189,"score_spread":0.2716766740931851,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}