{"id":"W4415496302","doi":"10.1136/bmjno-2025-anzan.102","title":"3549 Continuous ofatumumab treatment up to 7 years shows a consistent safety profile and delays disability progression in people with RMS","year":2025,"lang":"","type":"article","venue":"","topic":"Otitis Media and Relapsing Polychondritis","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Hotchkiss Brain Institute; University of Calgary","funders":"","keywords":"Ofatumumab; Safety profile; Test (biology); Data collection; Population","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005868126,0.0002607091,0.0007727646,0.0002288193,0.0002908064,0.0006112258,0.0002743584,0.0004739982,0.006497454],"category_scores_gemma":[0.001431275,0.000133102,0.0008190407,0.0003156851,0.0001908494,0.0004340432,0.0002050923,0.0007869933,0.001388491],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004118481,"about_ca_system_score_gemma":0.0003502891,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001376696,"about_ca_topic_score_gemma":0.003755613,"domain_scores_codex":[0.9994634,0.0001269387,0.0000416581,0.0000887594,0.000162798,0.0001164553],"domain_scores_gemma":[0.9992962,0.0002407501,0.0001640314,0.00005545855,0.000130474,0.0001131565],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.03673498,0.002718681,0.06380884,0.001452095,0.001433553,0.000386042,0.0001815305,0.0007681837,0.06067041,0.0003781188,0.01225915,0.8192085],"study_design_scores_gemma":[0.008712968,0.07492607,0.8459343,0.0005970093,0.001868076,0.003138873,0.000314282,0.001427103,0.01709948,0.0006658396,0.04520727,0.0001085228],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9488819,0.02737834,0.001435098,0.001186413,0.0003304562,0.0002230041,0.002134264,0.0002385197,0.0181922],"genre_scores_gemma":[0.992368,0.002512104,0.0008454277,0.0005840936,0.0001341268,0.00006506171,0.001130508,0.00001795215,0.002342735],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006497454,"threshold_uncertainty_score":0.02173609,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007055836162615023,"score_gpt":0.2790792580786718,"score_spread":0.2720234219160568,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}