{"id":"W4415496720","doi":"10.1016/j.ydbio.2025.10.019","title":"Development and regeneration of ectodermal Organs: A multiscale platform for topobiology","year":2025,"lang":"en","type":"article","venue":"Developmental Biology","topic":"Reproductive Biology and Fertility","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia","funders":"National Institutes of Health; Canada Research Chairs","keywords":"Morphogen; Epigenetics; Reprogramming; Morphogenesis; Enhancer; Regeneration (biology); Phenotype; Cell fate determination; Context (archaeology)","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003393647,0.0003681914,0.000585319,0.0006355194,0.0004906441,0.001732692,0.0007962445,0.0006798066,0.003111878],"category_scores_gemma":[0.0003810405,0.000381742,0.0004459839,0.0002997458,0.001445901,0.001554632,0.002335024,0.001432059,0.0006136242],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006816494,"about_ca_system_score_gemma":0.0006486514,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004458138,"about_ca_topic_score_gemma":0.0006934461,"domain_scores_codex":[0.9998203,0.00002697845,0.000007784961,0.00004858577,0.00006717732,0.00002923879],"domain_scores_gemma":[0.9997934,0.00004334898,0.00003140392,0.00004950935,0.00002311637,0.00005939032],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005156938,0.00007533866,0.001881062,0.0003536932,0.00006587758,0.0001998395,0.0002331235,0.01234271,0.787284,0.1158022,0.00175374,0.07995707],"study_design_scores_gemma":[0.00006406909,0.0006885134,0.02959557,0.0003461938,0.0001771461,0.001327853,0.001087061,0.1933651,0.25019,0.4001271,0.1227597,0.0002716267],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"methods","genre_gemma":"empirical","genre_scores_codex":[0.1888899,0.01142101,0.7675385,0.003540669,0.0005686993,0.00008740345,0.0006721095,0.001692099,0.02558962],"genre_scores_gemma":[0.8028374,0.007938715,0.1827252,0.0006066691,0.0002896777,0.0001506276,0.000293952,0.0002665747,0.004891183],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.003111878,"threshold_uncertainty_score":0.01041025,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02804701944216148,"score_gpt":0.298774927303313,"score_spread":0.2707279078611515,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}