{"id":"W4415500891","doi":"10.3390/immuno5040051","title":"IFN-τ Modulates PBMC Cytokine Profile and T Cell Phenotype to Improve Endometrial Immune Composition in the Implantation Window: A Combined In Vitro and In Vivo Study","year":2025,"lang":"en","type":"article","venue":"Immuno","topic":"Reproductive System and Pregnancy","field":"Immunology and Microbiology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"B.C. Women's Hospital & Health Centre; Women's Health Research Institute","funders":"European Commission","keywords":"Peripheral blood mononuclear cell; Immune system; Immunotherapy; In vitro; Cytokine; In vivo; T cell; Endometrium","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000475145,0.0003551683,0.0004227591,0.0001572448,0.0001057695,0.0002384339,0.0001410847,0.000236887,0.001262688],"category_scores_gemma":[0.0001783859,0.0001331645,0.0003334609,0.0001220358,0.0001852378,0.0001506595,0.000125783,0.0006277232,0.0003214816],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008606637,"about_ca_system_score_gemma":0.0001257935,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00009240826,"about_ca_topic_score_gemma":0.0002014683,"domain_scores_codex":[0.999743,0.0001118681,0.00001969384,0.00003936321,0.00003588744,0.00005013875],"domain_scores_gemma":[0.9999175,0.00002354831,0.00001354604,0.00001723633,0.00000969234,0.00001840262],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002403641,0.0005985335,0.0006830837,0.0001079809,0.00001388404,0.00006291625,0.00004480127,0.000086571,0.9886335,0.00001975612,0.00004019396,0.007305147],"study_design_scores_gemma":[0.0006277053,0.03976115,0.02788032,0.00003361972,0.0002113262,0.0007304509,0.0001604078,0.001217555,0.9254382,0.0000647234,0.003861251,0.00001317219],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9938366,0.003700761,0.00149532,0.00005848104,0.00007878825,0.00007824478,0.0001175845,0.0000136126,0.000620524],"genre_scores_gemma":[0.993947,0.002361523,0.001897802,0.00009105342,0.00008358274,0.0001258215,0.0002125779,0.000008428196,0.001272232],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001262688,"threshold_uncertainty_score":0.004224122,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006513855226995852,"score_gpt":0.2393544734402079,"score_spread":0.232840618213212,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}