{"id":"W4415504463","doi":"10.1021/acsnano.5c11682","title":"Pulmonary Surfactant Protein-Hitchhiking Inhalable Vaccines Augment Mucosal and Systemic Antiviral Immunity","year":2025,"lang":"en","type":"article","venue":"ACS Nano","topic":"Neonatal Respiratory Health Research","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"National Institute for Nanotechnology","funders":"National Key Research and Development Program of China; Chinese Academy of Medical Sciences; Chinese Academy of Sciences; National Natural Science Foundation of China","keywords":"Adjuvant; Immune system; Antibody; Antigen; Respiratory system; Immunization; Immunity; Lung","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001156513,0.0002850748,0.0002127392,0.0001262881,0.0000599038,0.0001985676,0.0001138705,0.0002999748,0.0009600362],"category_scores_gemma":[0.00008236259,0.00007774378,0.0002180366,0.00006506898,0.0001068272,0.0002230596,0.0002054323,0.0003970497,0.000212103],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001494366,"about_ca_system_score_gemma":0.0001440671,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002297407,"about_ca_topic_score_gemma":0.0005365469,"domain_scores_codex":[0.9999058,0.00001610185,0.000006546253,0.00001734923,0.00002829086,0.00002590309],"domain_scores_gemma":[0.9999658,0.000005200427,0.000009859296,0.000003697589,0.000007906257,0.000007514089],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006358712,0.00004703879,0.0001307532,0.00007536151,0.000005881489,0.00002449833,0.000008534118,0.0001457727,0.9910602,0.0001046267,0.0000752443,0.008258471],"study_design_scores_gemma":[0.00003169873,0.002008033,0.001939427,0.00001341715,0.00003920009,0.0001501272,0.00002118428,0.001754445,0.9863196,0.00007968551,0.007637836,0.000005351519],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9765773,0.01030785,0.009578228,0.0002662736,0.0001322071,0.0001156701,0.000164263,0.0001936875,0.002664416],"genre_scores_gemma":[0.9890718,0.002970621,0.0048523,0.0001335901,0.00004193652,0.00004286821,0.0001556683,0.00001358586,0.002717461],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009600362,"threshold_uncertainty_score":0.003211617,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02286039150160329,"score_gpt":0.3274465507262539,"score_spread":0.3045861592246506,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}