{"id":"W4415504463","doi":"10.1021/acsnano.5c11682","title":"Pulmonary Surfactant Protein-Hitchhiking Inhalable Vaccines Augment Mucosal and Systemic Antiviral Immunity","year":2025,"lang":"en","type":"article","venue":"ACS Nano","topic":"Neonatal Respiratory Health Research","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"National Institute for Nanotechnology","funders":"National Key Research and Development Program of China; Chinese Academy of Medical Sciences; Chinese Academy of Sciences; National Natural Science Foundation of China","keywords":"Adjuvant; Immune system; Antibody; Antigen; Respiratory system; Immunization; Immunity; Lung","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00081919,0.0001947122,0.0003921664,0.0002501063,0.0002487673,0.00003856529,0.0001647007,0.000133556,0.00002988844],"category_scores_gemma":[0.0003651082,0.0001636962,0.00004408125,0.0004961701,0.00006517649,0.0001515792,0.0003031557,0.0004371592,0.00004315471],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002392555,"about_ca_system_score_gemma":0.0006609325,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004221644,"about_ca_topic_score_gemma":0.00001456217,"domain_scores_codex":[0.9981537,0.0001775977,0.0004007863,0.000351277,0.0004017741,0.0005148202],"domain_scores_gemma":[0.9989256,0.0001540579,0.00007864428,0.0004995364,0.0001824574,0.0001597041],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007517585,0.0002055889,0.05046004,0.004678084,0.00007402115,0.000479442,0.00007891814,4.745391e-7,0.8712402,0.0005171518,0.0001559622,0.07135835],"study_design_scores_gemma":[0.007955996,0.001567661,0.1418425,0.008996323,0.0001950473,0.0009978046,0.001041012,0.0006774348,0.7861805,0.0009325569,0.04871286,0.0009003044],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9826266,0.01022749,0.0000190545,0.001194994,0.0001403891,0.00146841,0.000008740832,0.00008738849,0.004226919],"genre_scores_gemma":[0.9945547,0.0004296537,0.0001146814,0.0003054503,0.00005604779,0.0000971634,0.00001044816,0.00002411375,0.004407752],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.09138244,"threshold_uncertainty_score":0.6675337,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02286039150160329,"score_gpt":0.3274465507262539,"score_spread":0.3045861592246506,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}