{"id":"W4415519856","doi":"10.1016/j.jtho.2025.09.109","title":"MA02.06 Efficacy and Safety of 1L Olomorasib Plus Pembrolizumab in KRAS G12C-Mutant NSCLC: Results From LOXO-RAS-20001 and SUNRAY-01","year":2025,"lang":"en","type":"article","venue":"Journal of Thoracic Oncology","topic":"Cancer Immunotherapy and Biomarkers","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":false,"ca_institutions":"Princess Margaret Cancer Centre","funders":"","keywords":"Pembrolizumab; KRAS; MEDLINE; Immunotherapy; PD-L1","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004959104,0.0005319278,0.001191191,0.0003140976,0.0002448539,0.0007880323,0.0006070102,0.0006625351,0.003707584],"category_scores_gemma":[0.0003514239,0.0002596985,0.0008595379,0.0002007812,0.0005639951,0.0007134978,0.0001581874,0.002067416,0.001060449],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005627684,"about_ca_system_score_gemma":0.0008391556,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00126203,"about_ca_topic_score_gemma":0.002078965,"domain_scores_codex":[0.9997454,0.00007259386,0.00001734166,0.00004507907,0.00003018821,0.00008928661],"domain_scores_gemma":[0.9997968,0.00003025017,0.00003138813,0.00003003764,0.00001236975,0.00009914401],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.3813559,0.04038177,0.004501443,0.0004915765,0.001178041,0.0003412291,0.0002202508,0.002337399,0.3630365,0.0008478789,0.004419002,0.200889],"study_design_scores_gemma":[0.1051406,0.691214,0.04348124,0.00007332925,0.001797717,0.0009503312,0.000213985,0.007406344,0.1395207,0.0004331692,0.009647169,0.0001213618],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9960366,0.00134063,0.0001821627,0.0002088763,0.00009176354,0.00006594414,0.0004187391,0.00007688057,0.001578361],"genre_scores_gemma":[0.9953638,0.0006288331,0.0003007814,0.0001245683,0.0000657013,0.00007567202,0.0008062072,0.00001837929,0.002616038],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003707584,"threshold_uncertainty_score":0.01240313,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01890126430736262,"score_gpt":0.3817211829039664,"score_spread":0.3628199185966038,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}