{"id":"W4415520663","doi":"10.1016/j.jtho.2025.09.924","title":"P3.12.62 First-Line Osimertinib ± Platinum-Pemetrexed Chemotherapy for EGFR-Mutated Advanced NSCLC: FLAURA2 Non-Asian Country Cohort","year":2025,"lang":"en","type":"article","venue":"Journal of Thoracic Oncology","topic":"Lung Cancer Treatments and Mutations","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Princess Margaret Cancer Centre","funders":"","keywords":"Osimertinib; Cohort; Chemotherapy; Cohort study; MEDLINE","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002652938,0.0003527771,0.0003954623,0.000316765,0.0007595584,0.001121481,0.0003933672,0.0003904951,0.008682583],"category_scores_gemma":[0.000648985,0.0003749345,0.001106857,0.0008010097,0.0002154016,0.0006111364,0.0004740362,0.001466871,0.001317749],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004167177,"about_ca_system_score_gemma":0.0007429286,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0113586,"about_ca_topic_score_gemma":0.01290526,"domain_scores_codex":[0.9997413,0.00002127439,0.00001921658,0.00009293184,0.00003116237,0.00009427396],"domain_scores_gemma":[0.9996135,0.00003205283,0.0001442865,0.00004487197,0.00004046684,0.0001248189],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001489422,0.0001133465,0.9903693,0.00004006371,0.000376506,0.0005849992,0.0001257419,0.0001490374,0.00121475,0.0001396442,0.00231384,0.003083364],"study_design_scores_gemma":[0.000145506,0.0003798341,0.990711,0.00003141117,0.000557471,0.00178691,0.0007322826,0.0005140394,0.0003239049,0.0002381059,0.004551556,0.00002797142],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9898736,0.0003777974,0.0001744301,0.0001887075,0.00003270463,0.00002822956,0.006699189,0.00001883281,0.002606373],"genre_scores_gemma":[0.9927014,0.0001702626,0.00008152852,0.0002094893,0.00002739142,0.00004072631,0.004574961,0.0000300179,0.002164184],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0113586,"threshold_uncertainty_score":0.02904612,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01191241342935816,"score_gpt":0.4269445142671295,"score_spread":0.4150321008377713,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}