{"id":"W4415534221","doi":"10.1111/all.70107","title":"Protective Role for Itaconate During Inhaled Allergen Challenge","year":2025,"lang":"en","type":"article","venue":"Allergy","topic":"Asthma and respiratory diseases","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"Medical Research Council; Asthma and Lung UK; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; Imperial College London; National Institute for Health and Care Research; Wellcome Trust","keywords":"Allergen; Asthma; Inhalation; Allergy; Inflammation; Inhaled corticosteroids","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001738537,0.0003233138,0.0004119728,0.0001772024,0.0001768188,0.0003727452,0.0002784774,0.000407965,0.00163711],"category_scores_gemma":[0.0003023516,0.00008287477,0.000237321,0.0001046387,0.000283793,0.0001877507,0.0002462051,0.0005586748,0.0003067518],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000269629,"about_ca_system_score_gemma":0.0003346389,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004748713,"about_ca_topic_score_gemma":0.0007379787,"domain_scores_codex":[0.9998299,0.00003638139,0.00001099355,0.00003041496,0.00004583923,0.00004645177],"domain_scores_gemma":[0.9996635,0.00004314499,0.00008934735,0.00004156413,0.00006263051,0.000099761],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0019371,0.0001283285,0.003023187,0.00007251962,0.00002132278,0.0001272303,0.00002706412,0.0000288951,0.9915153,0.00002938881,0.00006484803,0.003024871],"study_design_scores_gemma":[0.000172989,0.008403456,0.1264939,0.00004853349,0.0001546498,0.001298881,0.0001684598,0.0007536725,0.8582466,0.0001125019,0.004131805,0.00001439683],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9967163,0.001792614,0.0005425288,0.00008891139,0.000033018,0.00003120914,0.0001772465,0.00005836637,0.0005597059],"genre_scores_gemma":[0.9985279,0.0003041267,0.0002912758,0.00006231036,0.0000155312,0.00001907751,0.0002150332,0.00000883732,0.000555965],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00163711,"threshold_uncertainty_score":0.005476654,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009068651924519862,"score_gpt":0.2657916356697959,"score_spread":0.256722983745276,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}