{"id":"W4415534221","doi":"10.1111/all.70107","title":"Protective Role for Itaconate During Inhaled Allergen Challenge","year":2025,"lang":"en","type":"article","venue":"Allergy","topic":"Asthma and respiratory diseases","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"Medical Research Council; Asthma and Lung UK; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; Imperial College London; National Institute for Health and Care Research; Wellcome Trust","keywords":"Allergen; Asthma; Inhalation; Allergy; Inflammation; Inhaled corticosteroids","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005187061,0.0001383411,0.0002240483,0.0001085853,0.0001259692,0.000008051647,0.00007935834,0.00009412249,0.0001319251],"category_scores_gemma":[0.00007727239,0.0001170661,0.0001462484,0.0001013408,0.00003710157,0.00004619187,0.00005245845,0.00009055742,0.00002219048],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004867269,"about_ca_system_score_gemma":0.0001358937,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001568708,"about_ca_topic_score_gemma":0.00003737331,"domain_scores_codex":[0.9991758,0.00002304353,0.0001757774,0.0002729456,0.0001072997,0.000245113],"domain_scores_gemma":[0.9994984,0.00002604553,0.00004141747,0.0002162317,0.0001115956,0.0001063384],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.02845886,0.00985513,0.005108063,0.007781247,0.01568564,0.002392347,0.01238278,0.0007447588,0.2988559,0.05299291,0.04602156,0.5197208],"study_design_scores_gemma":[0.01248036,0.001100886,0.07586744,0.0005878204,0.0001714825,0.00003230978,0.001985199,0.0007293161,0.03031648,0.005882454,0.8702227,0.0006235409],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9261661,0.008813372,0.0007978312,0.004552931,0.0003822322,0.002757014,0.0000316661,0.0003317995,0.05616703],"genre_scores_gemma":[0.9922565,0.00008315829,0.000104206,0.0004346394,0.0001854195,0.0005342474,0.00001470149,0.00002347394,0.006363709],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.8242012,"threshold_uncertainty_score":0.4773816,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009068651924519862,"score_gpt":0.2657916356697959,"score_spread":0.256722983745276,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}