{"id":"W4415566144","doi":"10.1021/acsabm.5c01641","title":"Engineered Niclosamide Loaded Nanofiber Platforms for Enhanced Antibacterial and Anticancer Efficacy","year":2025,"lang":"en","type":"article","venue":"ACS Applied Bio Materials","topic":"Electrospun Nanofibers in Biomedical Applications","field":"Materials Science","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Dalhousie University","funders":"Ministry of Education, India; National Institute of Technology Warangal","keywords":"Niclosamide; Nanofiber; HeLa; Biocompatibility; Cytotoxicity; Drug delivery; Polycaprolactone; Antibacterial activity","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0005421158,0.0003658749,0.0006235519,0.0001436656,0.0002708299,0.0002563023,0.0004783465,0.0003033878,0.0003490262],"category_scores_gemma":[0.0000585574,0.0003053363,0.00004908923,0.0003606917,0.0003532018,0.0001197768,0.0002159034,0.00006837187,0.00008485241],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008421576,"about_ca_system_score_gemma":0.0001147343,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000011561,"about_ca_topic_score_gemma":0.000001866323,"domain_scores_codex":[0.9975616,0.00001814052,0.0007100976,0.0007671599,0.0002463063,0.0006966591],"domain_scores_gemma":[0.9987358,0.0003017634,0.0002053875,0.0005438078,0.0000869653,0.0001262757],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004032655,0.00008288572,0.000002424082,0.0001319055,0.00003594213,3.426537e-7,0.00005465584,3.718383e-7,0.9698518,0.02670903,0.00124239,0.001485026],"study_design_scores_gemma":[0.002016674,0.00006310649,0.000563818,0.000054199,0.00007047814,0.000001942072,0.00001290047,0.000001275744,0.9836914,0.008146689,0.005028842,0.0003486509],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9834705,0.00007218442,0.01212189,0.0003967147,0.001125106,0.001742333,0.0003479854,0.0002706145,0.0004526869],"genre_scores_gemma":[0.9827083,0.00007912552,0.01506205,0.0005773744,0.0003757563,0.0006939203,0.000154022,0.00004311101,0.0003063407],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01856234,"threshold_uncertainty_score":0.9999399,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007402698963768439,"score_gpt":0.2551634981457103,"score_spread":0.2477607991819419,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}