{"id":"W4415567844","doi":"10.1007/978-1-0716-4824-7_14","title":"Mouse Models for Use in Cryptosporidium Infection Studies, Quantification of Parasite Burden Using Flow Cytometry, qPCR and Histopathology, and Confocal Imaging of Oocysts","year":2025,"lang":"en","type":"article","venue":"Methods in molecular biology","topic":"Parasitic Infections and Diagnostics","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University; McGill University Health Centre","funders":"","keywords":"Cryptosporidium parvum; Cryptosporidium; Parasite hosting; Protozoan parasite; Monoclonal antibody; Polyclonal antibodies; Digital polymerase chain reaction; Confocal microscopy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00285359,0.003356421,0.001739908,0.006078,0.001892549,0.002221992,0.002300257,0.003808673,0.01654507],"category_scores_gemma":[0.00125641,0.001301014,0.001860603,0.001549656,0.001343521,0.001815136,0.001067493,0.006651313,0.004919303],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001425263,"about_ca_system_score_gemma":0.001392595,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002596776,"about_ca_topic_score_gemma":0.007358929,"domain_scores_codex":[0.9977465,0.0003298593,0.0003040551,0.000596033,0.0006405878,0.00038288],"domain_scores_gemma":[0.9973243,0.0003636138,0.0006591788,0.000555316,0.0005921589,0.0005053313],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002357715,0.001891336,0.001866314,0.0006450436,0.0001552377,0.0004884182,0.000305082,0.0005180207,0.9723289,0.00391421,0.004426248,0.01110357],"study_design_scores_gemma":[0.0005974926,0.004066504,0.009425313,0.0005577743,0.0006389576,0.002485106,0.000330081,0.002445681,0.9003734,0.002300381,0.07663292,0.0001463749],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"methods","genre_scores_codex":[0.5376217,0.01459139,0.3069789,0.004655465,0.004218883,0.01109196,0.08331999,0.01087591,0.02664576],"genre_scores_gemma":[0.4812063,0.01548099,0.2818392,0.003489116,0.0004911487,0.02855906,0.06899765,0.003167631,0.1167689],"genre_candidate":"methods","genre_consensus":null,"teacher_disagreement_score":0.01654507,"threshold_uncertainty_score":0.05534875,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05546335408665306,"score_gpt":0.4233608170152459,"score_spread":0.3678974629285928,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}