{"id":"W4415568763","doi":"10.1515/med-2025-1278","title":"Association of SGLT2 inhibition with psychiatric disorders: A Mendelian randomization study","year":2025,"lang":"en","type":"article","venue":"Open Medicine","topic":"Diabetes Treatment and Management","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Aging","funders":"National Natural Science Foundation of China","keywords":"Mendelian randomization; Association (psychology); Anxiety; Genetic association; Genome-wide association study; Bipolar disorder; Randomization; MEDLINE","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006366402,0.0001107186,0.0004013549,0.0002636073,0.00005226038,0.00001379548,0.00006976257,0.00003283989,0.0001991042],"category_scores_gemma":[0.000102392,0.00007162718,0.00002626995,0.0007140132,0.00002203005,0.0001099715,0.00004892109,0.00005704132,0.000005990041],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001074203,"about_ca_system_score_gemma":0.00004733743,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002612043,"about_ca_topic_score_gemma":0.0003816566,"domain_scores_codex":[0.9990054,0.00006658916,0.0003073393,0.000196802,0.0003054205,0.0001184721],"domain_scores_gemma":[0.9993978,0.00005763853,0.0001894901,0.0002077298,0.0001099859,0.0000373975],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.004267346,0.004055148,0.8718178,0.0003000571,0.00218079,0.000008859148,0.001403316,0.00002575959,0.0003119994,0.001620877,0.06807274,0.04593533],"study_design_scores_gemma":[0.4119862,0.01706263,0.4995259,0.002420166,0.01319347,0.000001590254,0.01166353,0.0005119792,0.0007082753,0.003069069,0.03940366,0.0004534539],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.6553266,0.000438318,0.002860222,0.04107174,0.0004299252,0.009617907,0.000004037268,0.00007264133,0.2901786],"genre_scores_gemma":[0.9823408,0.0001260954,0.0004458797,0.0004970198,0.00004873058,0.0001545462,0.00009387205,0.000009728025,0.0162833],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4077189,"threshold_uncertainty_score":0.2920871,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007584839243533065,"score_gpt":0.2903611978589488,"score_spread":0.2827763586154157,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}