{"id":"W4415587348","doi":"10.1021/acsabm.5c00247","title":"Antibiotic-Loaded Calcium Crosslinked Alginate Wound Dressings Fabricated via Pressurized Gas eXpanded Liquids Technology in Combination with Supercritical Adsorptive Precipitation for Treating Methicillin-Resistant <i>Staphylococcus</i> Infections","year":2025,"lang":"en","type":"article","venue":"ACS Applied Bio Materials","topic":"3D Printing in Biomedical Research","field":"Engineering","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Vanguard College; McMaster University","funders":"Canadian Institutes of Health Research; Natural Sciences and Engineering Research Council of Canada; Government of Canada","keywords":"Antimicrobial; Fusidic acid; Supercritical fluid; Antibiotics; Precipitation; Solubility; Drug","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001093762,0.0002574948,0.0001335939,0.0001827105,0.00008902412,0.0002913392,0.0001402745,0.0002292362,0.0004408155],"category_scores_gemma":[0.0001388524,0.0001419994,0.0002118555,0.0001229996,0.0001417767,0.0002353348,0.0001407204,0.0002286117,0.0001336718],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001900844,"about_ca_system_score_gemma":0.0001529375,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004267939,"about_ca_topic_score_gemma":0.0008220569,"domain_scores_codex":[0.9999135,0.000008370629,0.000009473304,0.00001568724,0.00003420714,0.0000188587],"domain_scores_gemma":[0.9999242,0.00001293098,0.00003370621,0.000007721786,0.00001067444,0.00001064894],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001453809,0.000006717598,0.00004078797,0.00001786719,0.000001763381,0.00001892356,0.000008869048,0.00009638868,0.9986221,0.00002248019,0.00001288345,0.001136785],"study_design_scores_gemma":[0.000003414147,0.00009606554,0.0005378845,0.00000259233,0.000006958672,0.00004136936,0.00000877568,0.001119095,0.9976785,0.000007300224,0.000494541,0.000003449592],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9925562,0.001070458,0.005135924,0.00004590283,0.00002945512,0.00002135494,0.00005824039,0.000101889,0.0009804841],"genre_scores_gemma":[0.9941626,0.0005547188,0.004176061,0.0000301664,0.000009024037,0.00001522541,0.00003742651,0.00001364973,0.001001052],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0004408155,"threshold_uncertainty_score":0.001474619,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0152470238102584,"score_gpt":0.2937363915817754,"score_spread":0.278489367771517,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}