{"id":"W4415587348","doi":"10.1021/acsabm.5c00247","title":"Antibiotic-Loaded Calcium Crosslinked Alginate Wound Dressings Fabricated via Pressurized Gas eXpanded Liquids Technology in Combination with Supercritical Adsorptive Precipitation for Treating Methicillin-Resistant <i>Staphylococcus</i> Infections","year":2025,"lang":"en","type":"article","venue":"ACS Applied Bio Materials","topic":"3D Printing in Biomedical Research","field":"Engineering","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Vanguard College; McMaster University","funders":"Canadian Institutes of Health Research; Natural Sciences and Engineering Research Council of Canada; Government of Canada","keywords":"Antimicrobial; Fusidic acid; Supercritical fluid; Antibiotics; Precipitation; Solubility; Drug","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0009843789,0.0003514461,0.0006118799,0.0007893954,0.0002355591,0.0002175666,0.0003060665,0.0005744103,0.0000180661],"category_scores_gemma":[0.0007015476,0.0003215463,0.00004098994,0.001275589,0.000489894,0.0001714508,0.0001190035,0.000363114,0.000008169179],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000261097,"about_ca_system_score_gemma":0.0001011501,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008251097,"about_ca_topic_score_gemma":0.00001574019,"domain_scores_codex":[0.9975646,0.000118661,0.0007435341,0.0005532464,0.000320373,0.0006995696],"domain_scores_gemma":[0.9982622,0.0008982392,0.00006249103,0.0003508317,0.0003397864,0.0000865017],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005028389,0.0002060735,0.0001768277,0.0005608078,0.0001188636,0.000002615331,0.0002451083,0.0001113199,0.9919211,0.005235206,0.00004682504,0.0008724174],"study_design_scores_gemma":[0.003107576,0.0002123132,0.002244066,0.0003078442,0.0000685642,8.467147e-7,0.0001387892,0.0007491215,0.9873537,0.005343783,0.0001508412,0.0003225103],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.939962,0.00004899733,0.05610942,0.0006236925,0.0001939166,0.00202759,0.00006343003,0.0005647869,0.0004061386],"genre_scores_gemma":[0.9963894,0.00001356392,0.002437818,0.0000437688,0.0000395645,0.0007948384,0.0001798896,0.00006306381,0.00003802386],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05642744,"threshold_uncertainty_score":0.9999236,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0152470238102584,"score_gpt":0.2937363915817754,"score_spread":0.278489367771517,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}