{"id":"W4415599729","doi":"10.1021/acs.joc.5c01551","title":"Synthesis of Benzimidazol-2-ones by Oxidative Cyclization Ring Closure of Amido-Urea Precursors","year":2025,"lang":"en","type":"article","venue":"The Journal of Organic Chemistry","topic":"Synthesis of heterocyclic compounds","field":"Chemistry","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Toronto and Region Conservation Authority","funders":"Universitatea din București; Ministry of Education and Research, Romania","keywords":"Oxidative phosphorylation; Reagent; Amide; Ring (chemistry); Closure (psychology); Reaction mechanism; Reaction intermediate; Reaction conditions","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001517891,0.000454661,0.0002552275,0.0002113652,0.0001593494,0.00029755,0.0004149806,0.000323562,0.00208887],"category_scores_gemma":[0.0002087159,0.0001514391,0.0002139475,0.0001434686,0.0001336619,0.0003849599,0.0002864054,0.0004777295,0.0007937548],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002412546,"about_ca_system_score_gemma":0.0003383203,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002604965,"about_ca_topic_score_gemma":0.001130234,"domain_scores_codex":[0.9998872,0.00001546444,0.0000128682,0.00002251157,0.0000253674,0.00003649054],"domain_scores_gemma":[0.9999338,0.00000795902,0.00001951898,0.000005998886,0.00001434833,0.00001829544],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001468664,0.00009505557,0.0002072816,0.0005151432,0.00002228153,0.0008676416,0.0001257178,0.0008008089,0.9725577,0.002959085,0.0004063434,0.02129607],"study_design_scores_gemma":[0.00005205487,0.001094825,0.0009289865,0.00002989254,0.0000273617,0.0008232163,0.00004127866,0.001058743,0.9700493,0.0003651029,0.0254989,0.00003035636],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9040663,0.02613309,0.04179461,0.0004340666,0.000536993,0.0005353928,0.001139514,0.0004067388,0.02495329],"genre_scores_gemma":[0.9590195,0.007174847,0.02604092,0.0001324298,0.00007260255,0.0002144418,0.0005362579,0.0000315608,0.006777416],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00208887,"threshold_uncertainty_score":0.006987989,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005324152745849966,"score_gpt":0.2234771482765502,"score_spread":0.2181529955307003,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}