{"id":"W4415619535","doi":"10.1056/evidoa2500109","title":"Age and Treatment Intensification in Metastatic Hormone-Sensitive Prostate Cancer","year":2025,"lang":"en","type":"review","venue":"NEJM Evidence","topic":"Prostate Cancer Treatment and Research","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Cancer Research","funders":"","keywords":"Prostate cancer; Radiation therapy; Cancer; Clinical trial; Patient data; Chemotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00731038,0.0009320963,0.004159328,0.00136793,0.0002259147,0.001112974,0.0006138009,0.001047342,0.001830686],"category_scores_gemma":[0.01182757,0.00047261,0.01300507,0.001551413,0.000384714,0.0007028074,0.0004765436,0.001413703,0.0001004943],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001048994,"about_ca_system_score_gemma":0.001130833,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002528927,"about_ca_topic_score_gemma":0.004171508,"domain_scores_codex":[0.9964425,0.002461973,0.0004139334,0.0002817808,0.0002932351,0.000106439],"domain_scores_gemma":[0.9925148,0.005500915,0.001521636,0.0001633988,0.0001828324,0.0001164146],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"meta_analysis","study_design_gemma":"not_applicable","study_design_scores_codex":[0.05415003,0.0006266414,0.04780346,0.1715133,0.5419194,0.0002583945,0.0002747855,0.008822101,0.001587255,0.0009533332,0.002072822,0.1700185],"study_design_scores_gemma":[0.02966931,0.01619914,0.08816303,0.03150998,0.8175636,0.0005627048,0.0001613211,0.0026349,0.001021928,0.002331593,0.01008502,0.0000975257],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.064793,0.9327501,0.0004701215,0.0005930732,0.0002675108,0.0001527196,0.0002214779,0.00001551485,0.0007365748],"genre_scores_gemma":[0.6823783,0.3125766,0.001781757,0.001463844,0.0007676948,0.0003501302,0.0003462643,0.00001153255,0.0003239046],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.00731038,"threshold_uncertainty_score":0.03866142,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.181017516789616,"score_gpt":0.4610676770126741,"score_spread":0.2800501602230582,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}