{"id":"W4415620886","doi":"10.1002/jha2.70164","title":"Secondary Malignancies Following CAR T‐Cell Therapy for B‐Cell Malignancies: A Retrospective Analysis","year":2025,"lang":"en","type":"article","venue":"eJHaem","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University Medical Centre; Ontario Clinical Oncology Group; McMaster University; Juravinski Cancer Centre; Juravinski Hospital","funders":"Ontario Institute for Cancer Research; Government of Ontario; Leukemia and Lymphoma Society of Canada; Cancer Research Society","keywords":"Complication; Malignancy; Retrospective cohort study; Clinical trial; Adverse effect; MEDLINE","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0006890314,0.0003366685,0.0009224035,0.0007129291,0.0002483531,0.00008103493,0.000290383,0.0002010792,0.00200154],"category_scores_gemma":[0.00009421095,0.000300348,0.001216402,0.001945256,0.000110135,0.0001094022,0.00008594597,0.0003784318,0.00003618586],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004348801,"about_ca_system_score_gemma":0.0005678203,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001595706,"about_ca_topic_score_gemma":0.00006983911,"domain_scores_codex":[0.9975058,0.00008720995,0.0004379043,0.000726141,0.0005343196,0.0007086078],"domain_scores_gemma":[0.9982945,0.0002804884,0.0001022448,0.000838486,0.000318292,0.0001660248],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001410639,0.0008665012,0.1071141,0.0004498591,0.004595696,0.0002209056,0.004074442,0.00002358144,0.8511381,0.0005215468,0.02070079,0.008883924],"study_design_scores_gemma":[0.01322773,0.001928746,0.0673481,0.0002108864,0.002113041,0.000008900851,0.003875694,0.0006660828,0.7316574,0.001304829,0.1768977,0.0007608449],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9280654,0.006576405,0.002112777,0.0007984284,0.0004075873,0.00181144,0.00007746927,0.0001710388,0.05997947],"genre_scores_gemma":[0.8406456,0.0003705909,0.001222351,0.001107136,0.0001798634,0.0002910612,0.0000761964,0.00005728464,0.1560499],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1561969,"threshold_uncertainty_score":0.9999449,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01787858321658435,"score_gpt":0.3086770106493665,"score_spread":0.2907984274327821,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}