{"id":"W4415621744","doi":"10.1177/18796397251387208","title":"Morphological and functional phenotyping of skeletal muscle and bone in the zQ175 knock-in mouse model of Huntington's disease","year":2025,"lang":"en","type":"article","venue":"Journal of Huntington s Disease","topic":"Genetic Neurodegenerative Diseases","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval; Centre hospitalier de l'Université Laval","funders":"Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research; Biotechnology and Biological Sciences Research Council; Directorate for Biological Sciences","keywords":"Skeletal muscle; Atrophy; Contractility; Pathological; Sarcopenia; Peripheral; Disease; Muscle atrophy; Central nervous system","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004562813,0.0001977362,0.0003684571,0.0003718929,0.00009064631,0.00004984897,0.0002433074,0.00003913325,0.00001978379],"category_scores_gemma":[0.002344791,0.0001510365,0.0001532643,0.0003596178,0.0003644489,0.0002238229,0.0001740639,0.0002758444,4.534071e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002131176,"about_ca_system_score_gemma":0.0002443952,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000006941669,"about_ca_topic_score_gemma":0.00000424255,"domain_scores_codex":[0.9977906,0.0003412324,0.0007569333,0.0003509663,0.0005003146,0.0002599042],"domain_scores_gemma":[0.9985243,0.0004342164,0.0004677334,0.0002380733,0.000128017,0.0002076653],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0009707348,0.001516265,0.1341992,0.0003541961,0.00001383749,0.00003988246,0.0002888617,0.01585401,0.8420606,0.002484065,0.0001354,0.002082942],"study_design_scores_gemma":[0.002587355,0.0001042453,0.860818,0.000268296,0.0001582495,0.000003019331,0.0003396012,0.01727047,0.1138369,0.004318142,0.00004110268,0.0002546785],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9980388,0.0004365606,0.0003185892,0.0007415313,0.00007674697,0.0002226886,0.00006374053,0.000006335088,0.00009498237],"genre_scores_gemma":[0.9989589,0.000132901,0.000155379,0.0006255276,0.00004019169,0.000008686914,0.000001423762,0.00001305704,0.00006396371],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7282237,"threshold_uncertainty_score":0.615909,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02845844922859358,"score_gpt":0.2650139684017174,"score_spread":0.2365555191731238,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}