{"id":"W4415623131","doi":"10.1021/acsbiomaterials.5c00388","title":"Exploring Glomerular Filtration Mechanisms and Molecular Pathways: Insights for Advancing Hemodialysis Membrane Design","year":2025,"lang":"en","type":"review","venue":"ACS Biomaterials Science & Engineering","topic":"Dialysis and Renal Disease Management","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"St. Paul's Hospital; University of Toronto; St. Michael's Hospital; University of Saskatchewan","funders":"Social Sciences and Humanities Research Council of Canada","keywords":"Context (archaeology); Extracellular matrix; Membrane; Dialysis; Glomerulus; Kidney; Tissue engineering; Organ-on-a-chip; Podocyte","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005794731,0.0006910945,0.0009755224,0.001591905,0.0002590962,0.001067745,0.0007452662,0.001311223,0.002401197],"category_scores_gemma":[0.0005842458,0.0002559959,0.0004707508,0.001203413,0.000497569,0.001973936,0.0006876227,0.001817468,0.001221778],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000751591,"about_ca_system_score_gemma":0.001327348,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006724672,"about_ca_topic_score_gemma":0.00111489,"domain_scores_codex":[0.999853,0.00002595817,0.00001831369,0.00002546817,0.00006064194,0.0000165028],"domain_scores_gemma":[0.9997857,0.00009454042,0.00002511303,0.000009143909,0.00006264845,0.000022793],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00004773616,0.00009788269,0.0002072301,0.01858516,0.00009589596,0.0001910665,0.0001091437,0.0009768412,0.009423365,0.02582984,0.02269679,0.921739],"study_design_scores_gemma":[0.000009180656,0.0001047563,0.0005005809,0.002381271,0.00009481567,0.000675715,0.00006959438,0.0002879797,0.00191681,0.006269785,0.9876672,0.00002236089],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001828456,0.9971169,0.0008217451,0.0005110771,0.0001805151,0.000004998328,0.00001512302,0.00001351547,0.001153263],"genre_scores_gemma":[0.00101348,0.9973912,0.0007474835,0.0002187696,0.0001365806,0.000008211261,0.00002133232,0.000001781462,0.0004610878],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002401197,"threshold_uncertainty_score":0.008032799,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06343460563350142,"score_gpt":0.2799999055411587,"score_spread":0.2165652999076572,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}