{"id":"W4415625738","doi":"10.3390/cells14211692","title":"M1 Macrophages Are a Source of IL-1α: A Driver of Progesterone Metabolism and Myometrial Contraction","year":2025,"lang":"en","type":"article","venue":"Cells","topic":"Preterm Birth and Chorioamnionitis","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Sinai Health System; Lunenfeld-Tanenbaum Research Institute","funders":"Canadian Institutes of Health Research","keywords":"Intracellular; Contraction (grammar); Inflammation; Contractility; Metabolism; Monocyte; Uterine contraction; Uterus; Downregulation and upregulation","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002574695,0.0004625099,0.0003526756,0.0003704969,0.0003783835,0.000500823,0.0002026366,0.0005478716,0.001685637],"category_scores_gemma":[0.0002139365,0.0002090212,0.0003815659,0.0001963683,0.0003305502,0.0002506055,0.0004251253,0.0007852576,0.0009291437],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002834677,"about_ca_system_score_gemma":0.0002563327,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004217272,"about_ca_topic_score_gemma":0.0005350245,"domain_scores_codex":[0.9997275,0.00005899399,0.00001850721,0.00005278744,0.00004394936,0.00009823675],"domain_scores_gemma":[0.9998666,0.00001354815,0.00004158998,0.00001321965,0.00002632985,0.00003867289],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006316923,0.00008474018,0.003949645,0.0004142156,0.0000169225,0.0005269271,0.0002244919,0.00004772535,0.9850137,0.0004407549,0.0004474943,0.008201631],"study_design_scores_gemma":[0.0002480907,0.002921198,0.1369141,0.0002853443,0.0001814897,0.005534923,0.001485399,0.001105842,0.7835476,0.001316416,0.06642083,0.00003876426],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9292669,0.05594296,0.005494302,0.00172835,0.0002998894,0.0002215895,0.001008279,0.0001677519,0.005869857],"genre_scores_gemma":[0.9761111,0.01344823,0.002555575,0.0005044449,0.0002723753,0.000197263,0.0006127991,0.00002253474,0.006275653],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001685637,"threshold_uncertainty_score":0.005639076,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006874346670600743,"score_gpt":0.2402823192003255,"score_spread":0.2334079725297248,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}