{"id":"W4415668966","doi":"10.1016/j.htct.2025.104457","title":"RESULTS FROM VERIFY, A PHASE 3, DOUBLE-BLIND, PLACEBO-CONTROLLED STUDY OF RUSFERTIDE FOR THE TREATMENT OF POLYCYTHEMIA VERA","year":2025,"lang":"en","type":"article","venue":"Hematology Transfusion and Cell Therapy","topic":"Myeloproliferative Neoplasms: Diagnosis and Treatment","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre","funders":"","keywords":"Phlebotomy; Polycythemia vera; Clinical endpoint; Hematocrit; Placebo; Clinical trial; Randomized controlled trial","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001322588,0.0002382864,0.001011056,0.0001029377,0.0001312352,0.000006654876,0.00006367446,0.0001191046,0.0000834923],"category_scores_gemma":[0.000007716098,0.0001277176,0.0002136618,0.0001162566,0.00008652179,0.00001613088,0.0000051048,0.00006635217,8.11366e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002294616,"about_ca_system_score_gemma":0.00008557522,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004258874,"about_ca_topic_score_gemma":0.0002103901,"domain_scores_codex":[0.9986857,0.00008325106,0.0005938367,0.0003453075,0.0001266382,0.0001652709],"domain_scores_gemma":[0.9982273,0.001148323,0.0001309033,0.0003537432,0.00008175306,0.0000579696],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9153709,0.02591066,0.007145382,0.0000545306,0.002359327,0.00002211811,0.009769784,0.000005081454,0.01939051,0.0004663077,0.0001615927,0.01934383],"study_design_scores_gemma":[0.6303754,0.009993737,0.0008162857,0.00005844574,0.0007346899,0.000005325201,0.001490214,0.0001777762,0.3541073,0.00006432608,0.002094267,0.00008217785],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9863153,0.005676622,0.000202243,0.001466613,0.0001233715,0.005593108,0.00006424593,0.00001684356,0.0005417216],"genre_scores_gemma":[0.9842864,0.01391459,0.0001014454,0.0001482559,0.00002060722,0.001142715,0.00003801451,0.00001329702,0.0003346351],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3347168,"threshold_uncertainty_score":0.5208174,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04133502875619269,"score_gpt":0.3419187682989942,"score_spread":0.3005837395428015,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}