{"id":"W4415671112","doi":"10.1016/j.htct.2025.104836","title":"HEALTH-RELATED QUALITY OF LIFE IN PATIENTS WITH TRANSPLANT-INELIGIBLE OR TRANSPLANT-DEFERRED NEWLY DIAGNOSED MULTIPLE MYELOMA (MM) IN THE PHASE 3 CEPHEUS TRIAL","year":2025,"lang":"en","type":"article","venue":"Hematology Transfusion and Cell Therapy","topic":"Multiple Myeloma Research and Treatments","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Cancer Research; University of Calgary","funders":"","keywords":"Daratumumab; Multiple myeloma; Quality of life (healthcare); Bortezomib; Population; Clinical trial; Phases of clinical research","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005414277,0.0002754848,0.001094505,0.000319314,0.0001035609,0.000009631737,0.000140901,0.0002104588,0.0001074821],"category_scores_gemma":[0.00003454366,0.000154684,0.0001102591,0.0005603545,0.0001506192,0.0000526488,0.000004417066,0.0003532512,0.00000160027],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002841383,"about_ca_system_score_gemma":0.0003240675,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002591788,"about_ca_topic_score_gemma":0.004231137,"domain_scores_codex":[0.9971542,0.0006777421,0.000965867,0.0004126985,0.0003327363,0.0004567267],"domain_scores_gemma":[0.9987032,0.0006555301,0.0001211496,0.0003013781,0.000048074,0.0001706757],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.4213,0.007446949,0.551681,0.00042829,0.0001308632,0.0001416719,0.004399902,0.000002059883,0.0005359391,0.00005547843,0.00003644465,0.01384141],"study_design_scores_gemma":[0.5412269,0.003888395,0.451974,0.0003520758,0.00003037053,0.00001385631,0.0004237334,0.00009934162,0.0017092,0.0000352788,0.00009354497,0.0001533148],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9929097,0.001777356,0.0001261534,0.001517205,0.00006832102,0.003290781,0.00008561868,0.00002856339,0.0001963459],"genre_scores_gemma":[0.9933494,0.00561529,0.00007286935,0.0005105884,0.00000613604,0.0001807765,0.000198786,0.00001753367,0.00004860794],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1199268,"threshold_uncertainty_score":0.6307832,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03849506143546937,"score_gpt":0.3321415740261922,"score_spread":0.2936465125907228,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}