{"id":"W4415671960","doi":"10.1073/pnas.2524944122","title":"Testing paradox may explain increased observed prevalence of bacterial STIs among MSM on HIV PrEP: A modeling study","year":2025,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"Reproductive tract infections research","field":"Immunology and Microbiology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"Government of New Brunswick","funders":"Max-Planck-Gesellschaft; Bundesministerium für Bildung und Forschung; Deutsche Forschungsgemeinschaft","keywords":"Pre-exposure prophylaxis; Transmission (telecommunications); Men who have sex with men; Human immunodeficiency virus (HIV); Condom; Asymptomatic; Epidemiology; Public health","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001043979,0.0006240684,0.00096448,0.0007541591,0.000616516,0.001254718,0.001584541,0.001522912,0.003365864],"category_scores_gemma":[0.004156771,0.0003720437,0.001113649,0.0004640871,0.0006573235,0.001116026,0.001189391,0.001153114,0.0002192197],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001116215,"about_ca_system_score_gemma":0.001146703,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.02027528,"about_ca_topic_score_gemma":0.01469631,"domain_scores_codex":[0.9996971,0.0001498826,0.0000112207,0.00004959186,0.000013978,0.00007835269],"domain_scores_gemma":[0.9976998,0.001562918,0.0003236131,0.0001072028,0.0001238191,0.0001826516],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"simulation_or_modeling","study_design_gemma":"simulation_or_modeling","study_design_scores_codex":[0.0002611894,0.0003907609,0.04585259,0.0001044937,0.000186956,0.0006291891,0.0003943314,0.9131604,0.001355278,0.03186699,0.001686407,0.004111277],"study_design_scores_gemma":[0.00003864434,0.00005678443,0.002215485,0.000009410485,0.00003737217,0.00003744209,0.0001137126,0.9917087,0.00006762168,0.005447839,0.0002527793,0.00001425605],"study_design_candidate":"simulation_or_modeling","study_design_consensus":"simulation_or_modeling","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9758151,0.0002401366,0.01566772,0.001260009,0.0000274853,0.00005003696,0.0004516804,0.00006256309,0.006425324],"genre_scores_gemma":[0.9962928,0.0001340644,0.001888949,0.00009550253,0.00001484675,0.00004479487,0.0001081142,0.00001520529,0.001405786],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02027528,"threshold_uncertainty_score":0.04031456,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1051753491204099,"score_gpt":0.347755760433973,"score_spread":0.2425804113135631,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}