{"id":"W4415686751","doi":"10.1101/2025.10.28.685060","title":"Consensus Pituitary Atlas, a scalable resource for annotation, novel marker discovery and analyses in pituitary gland research","year":2025,"lang":"","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Single-cell and spatial transcriptomics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"Wellcome Trust","keywords":"Annotation; Cell type; Scalability; Identification (biology); Chromatin; Cell; Pituitary gland; Resource (disambiguation)","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.005149158,0.001647342,0.002031668,0.006384084,0.001386041,0.003667988,0.003648345,0.001152951,0.02289709],"category_scores_gemma":[0.007133381,0.001491724,0.001586847,0.005689356,0.0006791594,0.002405975,0.005123061,0.002266877,0.01900647],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001605319,"about_ca_system_score_gemma":0.00604864,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.006271917,"about_ca_topic_score_gemma":0.01321517,"domain_scores_codex":[0.9974852,0.000373527,0.0003148711,0.0006274935,0.0009845903,0.0002143233],"domain_scores_gemma":[0.9952331,0.001200691,0.0005257451,0.001453635,0.0009361273,0.0006507818],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001295996,0.00008282971,0.005520132,0.004071746,0.0007192321,0.0007878722,0.0005638234,0.00638955,0.1125013,0.01497227,0.7594796,0.09361567],"study_design_scores_gemma":[0.0006393447,0.0001626677,0.01704692,0.000556904,0.0004746778,0.00125921,0.0002594086,0.02411359,0.05924403,0.03638483,0.8595588,0.0002996406],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"dataset","genre_gemma":"empirical","genre_scores_codex":[0.007935475,0.002542707,0.2743314,0.0008010392,0.000399282,0.0003680982,0.5306224,0.1749104,0.008089264],"genre_scores_gemma":[0.02241171,0.001459746,0.2929848,0.000470656,0.0002397536,0.001491936,0.6596223,0.01763479,0.003684247],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.02289709,"threshold_uncertainty_score":0.07659841,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04465354349109141,"score_gpt":0.3001288650884389,"score_spread":0.2554753215973475,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}