{"id":"W4415706878","doi":"10.1073/pnas.2512460122","title":"WrtF from <i>Rhizobium tropici</i> CIAT 899 is a GT-A fold fucosyltransferase that binds its donor nonproductively","year":2025,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"Glycosylation and Glycoproteins Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta; University of Guelph; McGill University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Glycomics Network; Canadian Institutes of Health Research","keywords":"Fucosyltransferase; Glycosyltransferase; Monosaccharide; Tetrasaccharide; Trisaccharide; Glycosyl donor; Anomer; Glycobiology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000600358,0.0005564799,0.0003278855,0.0001820093,0.0001652382,0.0003059609,0.0002909057,0.0003143481,0.001120636],"category_scores_gemma":[0.00017308,0.0001410031,0.0002797353,0.0003227841,0.0001308468,0.0001859488,0.0001448718,0.0004813971,0.0007830566],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004901208,"about_ca_system_score_gemma":0.0002004862,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003978431,"about_ca_topic_score_gemma":0.003112266,"domain_scores_codex":[0.9999217,0.000005576943,0.000004523834,0.00002477749,0.00002524511,0.00001817876],"domain_scores_gemma":[0.9999009,0.00001169607,0.0000323783,0.00001212983,0.0000134539,0.00002936394],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007298853,0.00001528029,0.0005492605,0.0000416721,0.000005977635,0.0001018996,0.00001920896,0.0001045256,0.9971149,0.00005127971,0.0001227704,0.001800316],"study_design_scores_gemma":[0.0000255591,0.0001989435,0.01346028,0.00001034544,0.00002331932,0.001852722,0.00004845766,0.0009290114,0.9699166,0.0000675535,0.01344757,0.00001962285],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9888934,0.001134606,0.004697621,0.0001359043,0.00002847314,0.00003329114,0.002768857,0.0002397863,0.002067989],"genre_scores_gemma":[0.9592419,0.0008957268,0.01301194,0.000108267,0.00001407252,0.00002852981,0.02127308,0.0001257292,0.005300749],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003978431,"threshold_uncertainty_score":0.00791055,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03353261774906745,"score_gpt":0.3102358068939087,"score_spread":0.2767031891448413,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}