{"id":"W4415721452","doi":"10.5376/tgmb.2025.15.0023","title":"Metabolomic and Genomic Analysis of Theobromine Biosynthesis in <i>Theobroma cacao</i>","year":2025,"lang":"","type":"article","venue":"Tree Genetics and Molecular Breeding","topic":"Cocoa and Sweet Potato Agronomy","field":"Agricultural and Biological Sciences","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Theobromine; Metabolomics; Theobroma; Purine; Purine metabolism; Functional genomics; Biosynthesis; Fermentation","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001273376,0.0005363961,0.0004589181,0.001068305,0.0002847269,0.0004410315,0.0001616951,0.0002551407,0.0005376919],"category_scores_gemma":[0.0001455765,0.0001696785,0.0005427141,0.000989221,0.0001894096,0.0002468341,0.0002370196,0.0002806901,0.0001692043],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004620842,"about_ca_system_score_gemma":0.0003946714,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.007455267,"about_ca_topic_score_gemma":0.007485372,"domain_scores_codex":[0.9998976,0.000006210289,0.000005601184,0.00005048744,0.00002085491,0.00001917848],"domain_scores_gemma":[0.9998664,0.0000137193,0.00004152929,0.00001020027,0.00003200767,0.00003612776],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001851212,0.00001552366,0.002687831,0.00008054805,0.00001884518,0.0001113663,0.00006259505,0.00006180977,0.994137,0.00003125417,0.00002322325,0.002584901],"study_design_scores_gemma":[0.00003584636,0.000546122,0.5835389,0.00004485682,0.000413295,0.001283028,0.0006863035,0.003503227,0.4027913,0.0002427381,0.006839875,0.00007454703],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9930086,0.0008868694,0.001909625,0.00007124812,0.00001369605,0.00003481754,0.003294386,0.00007891549,0.0007017287],"genre_scores_gemma":[0.9812181,0.0007827828,0.00731183,0.0001002152,0.00001720493,0.00005691497,0.008210232,0.00007301242,0.002229638],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007455267,"threshold_uncertainty_score":0.01482373,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009441084161194052,"score_gpt":0.2127266251129242,"score_spread":0.2032855409517302,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}