{"id":"W4415749821","doi":"10.1097/hep.0000000000001594","title":"Satellite lesions versus intrahepatic metastasis in multifocal intrahepatic cholangiocarcinoma: Prognostic impact and genomic profiling","year":2025,"lang":"en","type":"article","venue":"Hepatology","topic":"Cholangiocarcinoma and Gallbladder Cancer Studies","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa","funders":"Chugai Pharmaceutical; Genentech; National Natural Science Foundation of China; National Key Research and Development Program of China; AstraZeneca","keywords":"Metastasis; Satellite; Profiling (computer programming); Stage (stratigraphy); Intrahepatic Cholangiocarcinoma; Distant metastasis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002259987,0.0003342019,0.0008425959,0.0005349421,0.0001164293,0.00002675677,0.000113568,0.000178253,0.00003143452],"category_scores_gemma":[0.0004185703,0.0002836183,0.0001660409,0.0005320116,0.0002381577,0.0000767239,0.0001598862,0.0004197224,0.00002433276],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003285376,"about_ca_system_score_gemma":0.0003391725,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006607079,"about_ca_topic_score_gemma":0.001109749,"domain_scores_codex":[0.9980212,0.0001463076,0.0005245049,0.0005695312,0.0001384528,0.0006000202],"domain_scores_gemma":[0.9988208,0.0004942691,0.00008318607,0.0003612553,0.00008023963,0.0001602328],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.000805634,0.0001571765,0.9716747,0.0002621706,0.0003822038,0.0002761629,0.000578452,0.000001933398,0.001033156,0.0003512111,0.00008900204,0.02438821],"study_design_scores_gemma":[0.004577123,0.000472278,0.989522,0.0001409871,0.0006060035,0.0001316632,0.000277486,0.002877784,0.0006099562,0.0002465386,0.0003030137,0.0002351967],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9770873,0.01931069,0.00008684869,0.001064485,0.0003780279,0.0009219827,0.00001578496,0.0000793303,0.001055546],"genre_scores_gemma":[0.9968048,0.001164359,0.001382567,0.0003032626,0.00005946194,0.0001641507,0.00004595197,0.00002839723,0.00004708283],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02415301,"threshold_uncertainty_score":0.9999616,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02850833380477329,"score_gpt":0.3320586179616432,"score_spread":0.3035502841568699,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}