{"id":"W4415756175","doi":"10.1101/2025.10.30.685681","title":"Chitosan-Polyphosphate Scaffold Loaded with Copper for Endodontic Regeneration: A Laboratory Study","year":2025,"lang":"","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Endodontics and Root Canal Treatments","field":"Dentistry","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Dalhousie University","funders":"Dalhousie University; Dalhousie Medical Research Foundation","keywords":"Scaffold; Viability assay; Pulp (tooth); Root canal; Dentin; Fibroblast; Cell growth; Tissue engineering; Chitosan","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006406872,0.0006615234,0.0005070176,0.0004096671,0.0003806442,0.0003953177,0.0004278027,0.0009928897,0.0007154772],"category_scores_gemma":[0.0003200718,0.0002225226,0.0006922527,0.0002684933,0.0006118375,0.0003398841,0.0002286163,0.0003556113,0.0001936248],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002886329,"about_ca_system_score_gemma":0.0003437832,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007644861,"about_ca_topic_score_gemma":0.0007340368,"domain_scores_codex":[0.9996481,0.00005497825,0.00003082924,0.00007560252,0.0001250113,0.00006550377],"domain_scores_gemma":[0.9994764,0.0001161096,0.000163163,0.00006054595,0.0001149652,0.00006885124],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001077223,0.000268319,0.00008941667,0.0001235214,0.000007575486,0.0001415206,0.00007068484,0.0001397918,0.9981118,0.00002606033,0.00001754046,0.0008960046],"study_design_scores_gemma":[0.00003413932,0.005692821,0.002290418,0.0000161735,0.00006080185,0.0003640229,0.0001148053,0.0008495628,0.9898705,0.00002489833,0.0006603973,0.00002156305],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9971499,0.0006824316,0.001596098,0.000025323,0.00002028295,0.00005106959,0.00003709154,0.00002220151,0.0004157315],"genre_scores_gemma":[0.9946569,0.0006491973,0.003430828,0.00002274356,0.0000139975,0.0000720192,0.00007350755,0.000008114307,0.001072721],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009928897,"threshold_uncertainty_score":0.003388345,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01679629895808691,"score_gpt":0.2480702753850195,"score_spread":0.2312739764269326,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}