{"id":"W4415759346","doi":"10.1002/slct.202503934","title":"Recent Advances in Quinoline Derivatives: Biological and Medicinal Insights","year":2025,"lang":"en","type":"article","venue":"ChemistrySelect","topic":"Synthesis and biological activity","field":"Chemistry","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Discovery Centre","funders":"","keywords":"Quinoline; Drug discovery; Drug; Flexibility (engineering); Drug development","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004918147,0.0004822362,0.0004688214,0.001000824,0.0001791917,0.0006350593,0.0003601566,0.0004505468,0.003183308],"category_scores_gemma":[0.000390387,0.000206381,0.000339011,0.0009221784,0.0002750268,0.000817999,0.0004859535,0.0008654416,0.001016292],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003567099,"about_ca_system_score_gemma":0.0003764396,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004165181,"about_ca_topic_score_gemma":0.0006047183,"domain_scores_codex":[0.9998896,0.00002179341,0.00001325163,0.00002924104,0.0000301769,0.00001592445],"domain_scores_gemma":[0.9998112,0.00006992238,0.00003979982,0.000008842173,0.0000509012,0.00001931027],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000376391,0.0002896205,0.0007958618,0.02817535,0.0001433978,0.0007781924,0.0002821182,0.00246122,0.06928222,0.02108957,0.01513147,0.8611945],"study_design_scores_gemma":[0.00003727657,0.0009711682,0.001842853,0.00129818,0.0002007748,0.002328383,0.0001539957,0.001098264,0.02198285,0.005905082,0.964124,0.00005708716],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.003151086,0.9911926,0.001189842,0.0004257187,0.000161701,0.000009760111,0.00006163146,0.00001895881,0.003788611],"genre_scores_gemma":[0.02442156,0.9722577,0.001215136,0.0003860418,0.0003394969,0.00001058823,0.00009950671,0.000004923917,0.001265158],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003183308,"threshold_uncertainty_score":0.0106492,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01988991399224256,"score_gpt":0.2756699224511938,"score_spread":0.2557800084589512,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}