{"id":"W4415760957","doi":"10.1111/pai.70237","title":"Single cell RNA‐seq analysis of hematopoietic cell types in 22q11.2 deletion syndrome reveals significant changes to non‐T cells","year":2025,"lang":"en","type":"article","venue":"Pediatric Allergy and Immunology","topic":"Congenital heart defects research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre for Addiction and Mental Health; University Health Network","funders":"Children's Hospital of Philadelphia","keywords":"Cell type; Gene; Cell; Haematopoiesis; Hematopoietic cell; Single-cell analysis; Phenotype","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001942356,0.0002308963,0.0002819005,0.0004254271,0.0002521466,0.0003772907,0.0001546284,0.0002917192,0.001259079],"category_scores_gemma":[0.000343928,0.000129649,0.0002995758,0.0002956399,0.0001950486,0.00007656872,0.0002057775,0.0002439959,0.0003634191],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001183563,"about_ca_system_score_gemma":0.0001540013,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008747356,"about_ca_topic_score_gemma":0.001785999,"domain_scores_codex":[0.9997926,0.00001515432,0.00001219418,0.0001003998,0.00004953851,0.00003008496],"domain_scores_gemma":[0.9998453,0.00006107164,0.00002671964,0.00001751418,0.00003016739,0.00001932802],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0003543575,0.00001775179,0.0403791,0.0001345684,0.00006690566,0.0004123567,0.0002281142,0.0004084872,0.9503304,0.00007456973,0.00047096,0.007122364],"study_design_scores_gemma":[0.00004009503,0.0004403711,0.6620119,0.00005189841,0.000236624,0.002836577,0.000744152,0.006263114,0.3179832,0.000466001,0.008884671,0.00004132201],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9879947,0.0008500066,0.004463884,0.00005739709,0.00002887343,0.00002456765,0.005940237,0.0001105103,0.0005297295],"genre_scores_gemma":[0.9820887,0.0004569358,0.007324487,0.0001798372,0.00002094232,0.0001104889,0.00827196,0.00008659068,0.001460039],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001259079,"threshold_uncertainty_score":0.004212081,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006623769885084642,"score_gpt":0.2362633114666226,"score_spread":0.2296395415815379,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}