{"id":"W4415768395","doi":"10.1097/icu.0000000000001179","title":"Toward autonomous discovery: agentic AI and the future of ophthalmic research","year":2025,"lang":"en","type":"article","venue":"Current Opinion in Ophthalmology","topic":"Artificial Intelligence in Healthcare and Education","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"","keywords":"Workflow; Paradigm shift; MEDLINE; Corporate governance; Research ethics; Session (web analytics)","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":["metaresearch"],"consensus_categories":[],"category_scores_codex":[0.02956788,0.0006850456,0.002014274,0.003502189,0.000901254,0.007069651,0.002234634,0.004374697,0.003514244],"category_scores_gemma":[0.06920073,0.0004381648,0.001883588,0.002985354,0.00466084,0.006037272,0.002652738,0.004618933,0.0009654109],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.004058019,"about_ca_system_score_gemma":0.0139842,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003272742,"about_ca_topic_score_gemma":0.004161564,"domain_scores_codex":[0.9791142,0.01469939,0.001651964,0.0009718166,0.003164635,0.0003980951],"domain_scores_gemma":[0.8657957,0.1151013,0.006073751,0.003025377,0.008694819,0.00130913],"domain_codex":null,"domain_gemma":"methods","domain_candidate":"methods","domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.0001511142,0.00004611919,0.001212348,0.04522762,0.0009672955,0.0003050906,0.0008277135,0.004825651,0.0004217924,0.2458641,0.05915532,0.6409958],"study_design_scores_gemma":[0.00007807922,0.0001174609,0.001016962,0.05423849,0.0006614851,0.0005555997,0.0006803247,0.004083304,0.0004149147,0.3464149,0.5916442,0.00009431211],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":null,"genre_codex":"review","genre_gemma":"commentary","genre_scores_codex":[0.0003946217,0.9262417,0.01224194,0.05594963,0.001705503,0.00006123682,0.00007289648,0.0000771904,0.003255222],"genre_scores_gemma":[0.02724751,0.922731,0.02329173,0.02123047,0.004200429,0.0002786198,0.0001219827,0.00004616861,0.0008521426],"genre_candidate":"commentary","genre_consensus":null,"teacher_disagreement_score":0.9704321,"threshold_uncertainty_score":0.1563718,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.3119249604853278,"score_gpt":0.5413460373974998,"score_spread":0.229421076912172,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}