{"id":"W4415782400","doi":"10.1097/fpc.0000000000000579","title":"Pharmacogenetic testing coverage by Canadian insurance providers","year":2025,"lang":"en","type":"article","venue":"Pharmacogenetics and Genomics","topic":"Pharmacogenetics and Drug Metabolism","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Alberta Children's Hospital; University of Calgary; Dalhousie University","funders":"","keywords":"Reimbursement; Test (biology); Genetic testing; Quality (philosophy); Pharmacogenetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00074306,0.0006261441,0.0005153706,0.0004153385,0.0008498707,0.0001609412,0.0006379326,0.0003562144,0.0003486993],"category_scores_gemma":[0.00009903865,0.0007047401,0.0001272099,0.000711166,0.0003576802,0.0001149198,0.0002479287,0.000924685,0.00008387835],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002032698,"about_ca_system_score_gemma":0.0008536254,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001670086,"about_ca_topic_score_gemma":0.0005847298,"domain_scores_codex":[0.9965457,0.0003327079,0.0007407301,0.0008787508,0.0002171878,0.001284965],"domain_scores_gemma":[0.9976991,0.0003547741,0.0001924548,0.0003292389,0.0002523349,0.001172143],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001653249,0.000204438,0.03483321,0.0001396984,0.0004728559,0.0000471849,0.0003048858,0.002327883,0.5799131,0.0002893143,0.034203,0.3470991],"study_design_scores_gemma":[0.003290126,0.00004337593,0.002827739,0.00001693274,0.0003776838,0.00002667329,0.00003526415,0.01256734,0.170999,0.0008952947,0.8082501,0.0006704471],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9300575,0.0396687,0.0005441573,0.00235402,0.002669882,0.001173336,0.001163531,0.0001307525,0.0222381],"genre_scores_gemma":[0.9621878,0.01546194,0.0006344501,0.01925654,0.0003002942,0.0001259698,0.0000720041,0.00008091931,0.001880098],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7740471,"threshold_uncertainty_score":0.9995404,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06169952826165205,"score_gpt":0.3837315103934607,"score_spread":0.3220319821318087,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}