{"id":"W4415793065","doi":"10.1161/circ.152.suppl_3.4364679","title":"Abstract 4364679: Endothelial ADAM17 is essential in recovery from myocardial infarction by limiting cell death, promoting vascularization and optimizing infarct formation","year":2025,"lang":"en","type":"article","venue":"Circulation","topic":"Cardiac Fibrosis and Remodeling","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University Health Network; University of Alberta","funders":"","keywords":"Myocardial infarction; Endothelial stem cell; Ligation; Apoptosis; Immune system; Cardiac function curve; Troponin complex; Endothelium; Ventricular remodeling","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002926052,0.000763492,0.0007610371,0.0003701776,0.0003576509,0.0006306472,0.0004516685,0.0006924714,0.01877525],"category_scores_gemma":[0.0001537108,0.0002658202,0.0004215293,0.0002574984,0.0004970775,0.0004151597,0.0004111895,0.001400851,0.004990411],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003330037,"about_ca_system_score_gemma":0.0004853033,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004237811,"about_ca_topic_score_gemma":0.0004207817,"domain_scores_codex":[0.9997154,0.00003828316,0.0000374603,0.00006805512,0.00008033029,0.00006045627],"domain_scores_gemma":[0.9997025,0.00001870091,0.00009246008,0.00002314043,0.00003626598,0.0001269625],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001367276,0.00008655233,0.0003916875,0.0003604657,0.00002449626,0.0003418683,0.00002817612,0.00008407217,0.9897597,0.0004147385,0.001348168,0.005792751],"study_design_scores_gemma":[0.0003462688,0.001223992,0.01590326,0.0001221797,0.0001290222,0.002221084,0.0001417999,0.0006907702,0.9406681,0.000396407,0.03813793,0.00001913459],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9305768,0.01509099,0.01310069,0.003248098,0.001234169,0.000237328,0.0160672,0.001917407,0.01852748],"genre_scores_gemma":[0.9081835,0.008009024,0.006812911,0.0008136025,0.0004853042,0.0003085034,0.01181365,0.0004426598,0.06313084],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01877525,"threshold_uncertainty_score":0.06280947,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01003560979998926,"score_gpt":0.2360776857218939,"score_spread":0.2260420759219047,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}