{"id":"W4415794669","doi":"10.1161/circ.152.suppl_3.4365838","title":"Abstract 4365838: Survodutide for the Treatment of Obesity: Baseline characteristics of the SYNCHRONIZE Cardiovascular Outcomes Trial","year":2025,"lang":"en","type":"article","venue":"Circulation","topic":"Diabetes Treatment and Management","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"Placebo; Myocardial infarction; Clinical endpoint; Heart failure; Body mass index; Stroke (engine); Dyslipidemia; Diabetes mellitus; Type 2 diabetes","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001877411,0.0008639391,0.001442027,0.0002227326,0.0002509816,0.0006810919,0.0003193092,0.0009160641,0.006268159],"category_scores_gemma":[0.001555883,0.0002369561,0.001189614,0.0003331828,0.0003852526,0.0004819421,0.0003116959,0.001519984,0.0004993975],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002117795,"about_ca_system_score_gemma":0.0005949592,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003068796,"about_ca_topic_score_gemma":0.0008818188,"domain_scores_codex":[0.9994949,0.0002909423,0.00004740191,0.00006335085,0.00005840808,0.00004500953],"domain_scores_gemma":[0.9995121,0.0001297619,0.0001381097,0.00003388515,0.00004513414,0.000140975],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.9513142,0.002442757,0.005839357,0.001310371,0.001710089,0.00005115999,0.00004278122,0.0005487871,0.004207193,0.0002837078,0.004789323,0.02746025],"study_design_scores_gemma":[0.926089,0.04082264,0.02469597,0.0001728021,0.002481741,0.00009712346,0.00003184998,0.0007223235,0.0007622984,0.0004344001,0.003659628,0.00003020221],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9541736,0.01864414,0.001421134,0.002319667,0.000686263,0.004378232,0.008686278,0.0001712911,0.009519439],"genre_scores_gemma":[0.9740852,0.00486321,0.00194625,0.002020872,0.000627068,0.005323707,0.006657552,0.00003288288,0.004443293],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006268159,"threshold_uncertainty_score":0.02096915,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02412429568200366,"score_gpt":0.2719068611174049,"score_spread":0.2477825654354013,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}