{"id":"W4415828499","doi":"10.1016/j.molp.2025.10.022","title":"From synthetic small molecules to natural substances: The C4 photosynthetic pathway as a target for sustainable weed control","year":2025,"lang":"en","type":"article","venue":"Molecular Plant","topic":"Photosynthetic Processes and Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Ministerium für Kultur und Wissenschaft des Landes Nordrhein-Westfalen; Ontario Ministry of Research, Innovation and Science; Deutsche Forschungsgemeinschaft","keywords":"Phosphoenolpyruvate carboxylase; Photosynthesis; Weed; Agriculture; Pyruvate carboxylase; Small molecule; Enzyme","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003319595,0.0003811038,0.0003543643,0.00008586532,0.0002535441,0.0001233944,0.0007375121,0.000188783,0.00002003651],"category_scores_gemma":[0.0005171685,0.0002893288,0.0002547278,0.0001947677,0.00008016612,0.000005117754,0.0001731698,0.0001537893,0.00001437275],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004126376,"about_ca_system_score_gemma":0.0003125407,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002761951,"about_ca_topic_score_gemma":0.00009926879,"domain_scores_codex":[0.9978617,0.0001118853,0.0003273495,0.0007635936,0.000202694,0.0007328073],"domain_scores_gemma":[0.9986723,0.0001056877,0.0001057323,0.0007506209,0.0002192316,0.0001464124],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006535553,0.00008503511,0.000001150558,0.00006394687,0.000196739,0.00007603268,0.00009216019,0.0002128668,0.9895669,0.007931381,0.0004716433,0.0006485856],"study_design_scores_gemma":[0.0009329195,0.0002445919,0.000002320337,0.00008051114,0.00009128548,0.00001477154,0.0006092764,0.001029431,0.8366765,0.009904814,0.1500919,0.0003216198],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.693066,0.004336747,0.2934781,0.002192235,0.0005913185,0.003325411,0.0007004337,0.00007274377,0.002236947],"genre_scores_gemma":[0.991144,0.00002774362,0.001398047,0.003857544,0.00008721007,0.001167936,0.0002860052,0.00005181522,0.001979681],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.298078,"threshold_uncertainty_score":0.9999559,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003371851350308343,"score_gpt":0.2071727546764285,"score_spread":0.2038009033261201,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}