{"id":"W4415871235","doi":"10.1136/jitc-2025-sitc2025.1305","title":"1305 Coformulation of favezelimab and pembrolizumab as neoadjuvant therapy for resectable cutaneous squamous cell carcinoma (cSCC): Results from cohort a of the phase 2 keyform-010 study","year":2025,"lang":"","type":"article","venue":"","topic":"Nonmelanoma Skin Cancer Studies","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Jewish General Hospital; Centre hospitalier universitaire de Québec","funders":"","keywords":"Pembrolizumab; Cohort; Neoadjuvant therapy; Basal cell; Cohort study; Chemotherapy; Carcinoma","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0007688343,0.0007386373,0.001893853,0.0003370544,0.0005099914,0.00004862022,0.0005282651,0.0003154174,0.0001625452],"category_scores_gemma":[0.0006821324,0.0005187966,0.00037313,0.0007719583,0.0005142273,0.0001620891,0.0004645296,0.0004562638,0.000003433128],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003882532,"about_ca_system_score_gemma":0.001092413,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01406698,"about_ca_topic_score_gemma":0.001331529,"domain_scores_codex":[0.9944429,0.000247566,0.002299102,0.001204335,0.001001785,0.0008043526],"domain_scores_gemma":[0.9938825,0.002171131,0.001101309,0.001755434,0.0009284221,0.0001611797],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.2109521,0.01564656,0.6676947,0.001658596,0.00298043,0.0001517322,0.03130405,0.0002151754,0.02993313,0.0003863042,0.006753945,0.03232317],"study_design_scores_gemma":[0.225666,0.03382616,0.4491989,0.0007005493,0.003556715,0.00007027706,0.01901472,0.01043438,0.2522929,0.001059059,0.003225605,0.0009547419],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9581195,0.01090021,0.000134094,0.000592246,0.000927825,0.01082226,0.001281109,0.00003046222,0.01719233],"genre_scores_gemma":[0.9928409,0.001031581,0.0002289161,0.0002104461,0.0001972454,0.0002703372,0.00008395084,0.00007263717,0.005063943],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2223598,"threshold_uncertainty_score":0.9997264,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01525870662163638,"score_gpt":0.3050002982557685,"score_spread":0.2897415916341322,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}