{"id":"W4415879661","doi":"10.1016/j.chest.2025.10.030","title":"Examining the Threat of H5N1 Highly Pathogenic Avian Influenza to Human Health","year":2025,"lang":"en","type":"review","venue":"CHEST Journal","topic":"Influenza Virus Research Studies","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Guelph; University of Toronto; Sunnybrook Hospital; Canada Research Chairs; Sunnybrook Health Science Centre","funders":"Canadian Institutes of Health Research; University of Guelph; Chicken Farmers of Saskatchewan; Egg Farmers of Canada; Public Health Agency of Canada; Natural Sciences and Engineering Research Council of Canada; Ontario Agri-Food Innovation Alliance; Canadian Poultry Research Council","keywords":"Influenza A virus subtype H5N1; Human health; Highly pathogenic; Disease; Preparedness; Transmission (telecommunications); One Health; Animal health; Human animal","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001074938,0.0004520964,0.0007466481,0.002056122,0.0002607161,0.001272859,0.000496051,0.001649361,0.005596526],"category_scores_gemma":[0.00391633,0.0001963662,0.000552893,0.001213121,0.0002890002,0.001302377,0.000658764,0.001123053,0.001100431],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007377919,"about_ca_system_score_gemma":0.002088969,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003747266,"about_ca_topic_score_gemma":0.00461256,"domain_scores_codex":[0.9995975,0.0001409727,0.00007844553,0.00004688692,0.0001068749,0.00002935015],"domain_scores_gemma":[0.9974712,0.001455118,0.0003930522,0.00002379847,0.0004941889,0.0001625744],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00008800272,0.00002464122,0.001600555,0.06561892,0.0002907972,0.0002840611,0.0004283443,0.0002032712,0.0005819818,0.001735205,0.1255514,0.8035929],"study_design_scores_gemma":[0.00002292935,0.0001947202,0.007343133,0.08357894,0.0007583317,0.001712589,0.00101824,0.0001641181,0.0003279141,0.001891888,0.9029531,0.00003413565],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002780847,0.9936632,0.0000777256,0.002867417,0.001573395,0.00001077054,0.00007411028,0.000007069161,0.00144816],"genre_scores_gemma":[0.002192074,0.9943178,0.0001072016,0.001362127,0.001506547,0.00001243696,0.00005918437,0.000002292493,0.0004402798],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.005596526,"threshold_uncertainty_score":0.01872224,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.3160467424378177,"score_gpt":0.4918592318384085,"score_spread":0.1758124894005908,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}