{"id":"W4415896261","doi":"10.1111/dom.70196","title":"Survodutide for treatment of obesity: Baseline characteristics of participants in a randomized, double‐blind, placebo‐controlled, phase 3 trial ( <scp>SYNCHRONIZE</scp> ™‐1)","year":2025,"lang":"en","type":"article","venue":"Diabetes Obesity and Metabolism","topic":"Diabetes Treatment and Management","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University; University of Toronto","funders":"Boehringer Ingelheim","keywords":"Tolerability; Cohort; Weight loss; Baseline (sea); Cohort study; Obesity","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003436954,0.001012906,0.001643131,0.0003034142,0.0005517096,0.0007888062,0.0003925657,0.001343808,0.004408169],"category_scores_gemma":[0.002566226,0.0004527337,0.001211922,0.0003742682,0.0006858433,0.0007700326,0.0002608039,0.001384293,0.0005288929],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003126716,"about_ca_system_score_gemma":0.001060226,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005064117,"about_ca_topic_score_gemma":0.00100312,"domain_scores_codex":[0.9987611,0.0006419753,0.0001417193,0.0001846575,0.0001237247,0.0001469186],"domain_scores_gemma":[0.9990357,0.000220129,0.0002806772,0.00005947097,0.00008817601,0.0003158282],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9579415,0.007133652,0.01158291,0.0006170347,0.001017565,0.00006560162,0.0001029782,0.000317566,0.005641522,0.00008828058,0.001699962,0.01379147],"study_design_scores_gemma":[0.7333106,0.1861419,0.07164551,0.000166796,0.001845475,0.0001865174,0.0001424807,0.001061137,0.001473763,0.0003265592,0.003625789,0.00007353105],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9830215,0.003833935,0.0008251808,0.0003767874,0.0002035056,0.006218856,0.003486714,0.00004344726,0.001990001],"genre_scores_gemma":[0.977933,0.001392632,0.001749073,0.001084262,0.0001642788,0.01328837,0.002440709,0.00001850597,0.001929014],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004408169,"threshold_uncertainty_score":0.01817656,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0284267850544073,"score_gpt":0.3082491413655942,"score_spread":0.2798223563111868,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}